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Methods Inf Med 1997; 36(04/05): 254-256
DOI: 10.1055/s-0038-1636876
Original Article
Schattauer GmbH

Spatial Fluctuation of Regional Myocardial Blood Flows

T. Matsumoto
1   Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki, Okayama, Japan
,
J. Ebata
1   Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki, Okayama, Japan
,
K. Tsujioka
1   Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki, Okayama, Japan
,
Y. Ogasawara
1   Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki, Okayama, Japan
,
F. Kajiya
1   Department of Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki, Okayama, Japan
› Author Affiliations
Further Information

Publication History

Publication Date:
19 February 2018 (online)

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Abstract:

Digital radiography (100 pixels/mm2) combined with the technique of 3H-labeled desmethylimipramine deposition was employed to visualize regional blood flow distributions in rabbit left ventricular myocardium. A fluctuated pattern of myocardial flow and its dependence on arterial oxygen tension (PaO2) was evaluated with the coefficient of variation (CV) computed at each step of coarse-graining; flow images were revisualized by increasing pixel area (PA) step by step from 0.01 to 1 mm2. The CV values decreased with hypoxia at all resolution levels, suggesting that there is a vascular regulatory mechanism for making myocardial perfusion uniform in response to decreased PaO2. In both perfusion states, Cl/decreased with increasing PA. The relationship between CV and PA fitted the noninteger power law function, implying an apparent fractality of CV.

Keywords:

Radioactive Molecular Flow Marker - Hypoxia - Vasoregulation - Fractal
 

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