J Knee Surg 2018; 31(10): 999-1006
DOI: 10.1055/s-0038-1632378
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Kinematically Aligned Total Knee Arthroplasty or Mechanically Aligned Total Knee Arthroplasty

Tsuneari Takahashi
1  Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, West Yorkshire, United Kingdom
2  Department of Orthopaedic Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan
Juned Ansari
3  Department of Orthopaedic Surgery, Chapel Allerton Hospital, Leeds, West Yorkshire, United Kingdom
Hemant G. Pandit
1  Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, West Yorkshire, United Kingdom
› Author Affiliations
Funding None.
Further Information

Publication History

14 August 2017

07 January 2018

Publication Date:
14 February 2018 (eFirst)


Kinematically aligned total knee arthroplasty (KATKA) was developed to more anatomically align the knee prosthesis to restore the native alignment of the knee and promote physiological kinematics. Even though there are concerns with implant survival, and follow-up at 10 years or more after KATKA has not been reported, there is a negligible incidence of failure of a tibial component at 2 to 9 years. Early clinical results with this technique are encouraging and demonstrate better functional outcomes compared with mechanically aligned TKA (MATKA). The purpose of this study is to perform a systematic review and meta-analysis of the literature to determine whether there are any clinical differences between KATKA and MATKA. The authors conducted a systematic review of the English literature. Five randomized controlled trials (RCTs) which compared clinical outcomes of KATKA and MATKA were finally included. Four RCTs used patient-specific instrument, and one RCT used navigation. Data were extracted and meta-analysis was conducted. KATKA patients had better outcomes: Mean difference between KATKA and MATKA and p-value are presented in brackets after each variable: the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) (–12.5; p < 0.0001), Oxford Knee Score (OKS) (2.3; p = 0.030), combined Knee Society Score (C-KSS) (13.1; p < 0.0001), Knee Function Score (KFS) (6.4; p = 0.0070), and postoperative range of motion (ROM) (4.1°; p = 0.0010). There was no significant difference concerning the complication rates which needed reoperations or revision surgery (odds ratio, 1.01; p = 0.99). KATKA components had a more femoral valgus (–1.8°; p < 0.0001), more tibial varus (1.2°; p = 0.0001), and more tibial slope (1.2°; p = 0.0001), all being statistically significantly different. Better clinical outcomes were obtained in KATKA and component placement in KATKA is significantly different from that in MATKA. There was no increase of patients with poor clinical results due to implant position especially for varus placement of tibial component. This systematic review of five RCTs suggests that KATKA is of potential alternative method to MATKA since the risk of revision for tibial loosening is negligible compared with MATKA for the same follow-up period.

Authors' Contributions

T.T., J.A., and H.P. designed the study, conducted literature search, systematic review of the literature, and statistical analysis. All authors read and approved the final manuscript.

Ethical Approval

This is a systematic review so ethical approval was waived.