Absence of the Prothrombin Gene Variant in Koreans

• References

• 1 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and increase in venous thrombosis. Blood 1996; 88: 3698-703.
• 2 Bentolila S, Ripoll L, Drouet L, Mazoyer E. Thrombophilia due to 20210 G->A prothrombin polymorphism and cerebral ischemia in the young. Stroke 1997; 28: 1846-7.
• 3 Rosendaal FR, Siscovick DS, Schwartz SM, Psaty BM, Raghunathan TE, Vos HL. A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women. Blood 1997; 90: 1747-50.
• 4 Koelman BPC, Reitsma PH, Allaart CF, Bertina RM. Activated protein C resistance as an additional risk factor for thrombosis in protein C deficient families. Blood 1994; 84: 1031-4.
• 5 Song KS, Choi CR, Park Q, Lee A. Very low incidence of Arg506->Gln mutation in the factor V gene among Korean population. Thromb Haemost 1997. suppl 223
• 6 Kim YW, Yoon KY, Park S, Shim YS, Cho I H, Park SS. Absence of factor V Leiden mutation in Koreans. Thromb Res 1997; 86: 181-2.
• 7 Makris M, Preston FE, Beauchamp NJ, Cooper PC, Daly ME, Hampton KK, Bayliss P, Peake IR, Miller GJ. Co-inheritance of the 20210A allele of the prothrombin gene increases the risk of thrombosis in subjects with familial thrombophilia. Thromb Haemost 1997; 78: 1426-9.