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CC BY ND NC 4.0 · SynOpen 2019; 03(01): 4-10
DOI: 10.1055/s-0037-1611666
DOI: 10.1055/s-0037-1611666
paper
Highly Regio- and Stereoselective Hydrogermylation of Fluorinated Alkyl Propiolate
Authors
Further Information
Publication History
Received: 03 December 2018
Accepted: 04 January 2019
Publication Date:
28 January 2019 (online)
Abstract
The selective introduction of fluoroalkylated vinylmetals in controlled strategies is a challenging process for many chemists. This study reports the highly regio- and stereoselective synthesis of functionalized vinylgermanes bearing a perfluoroalkyl group from perfluoroalkylated acetylenic esters via AlCl3-catalyzed hydrogermylation. Regio- and stereoselectivity are highly dependent on the nature of the catalyst and the nature of the fluoroalkyl group of alkyne.
Key words
regio- and stereoselective hydrogermylation - fluorinated ethyl propiolate - AlCl3 - triphenyl- and tributylgermanes - fluorinated vinylgermanesSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1611666.
- Supporting Information (PDF)
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For Lewis acid catalyzed hydrosilylation, see: