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Synfacts 2018; 14(10): 0999
DOI: 10.1055/s-0037-1610902
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of a Phosphoinositide 3-Kinase (PI3K) β Inhibitor

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
17 September 2018 (online)

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Key words

phosphoinositide 3-kinase β inhibitor - aldehyde oxidase - atropisomers - benzimidazole ring formation - 1,2,4-triazole ring formation - Suzuki–Miyaura coupling