Stereoselective Reactions of ortho-Quinone Methide and ortho-Quinone Methide Imines and Their Utility in Natural Product Synthesis

Christian D.-T. Nielsen; Hossay Abas; Alan C. Spivey

doi:10.1055/s-0037-1610241

Synthesis, Table of Contents

Synthesis 2018; 50(20): 4008-4018
DOI: 10.1055/s-0037-1610241

short review

Stereoselective Reactions of ortho-Quinone Methide and ortho-Quinone Methide Imines and Their Utility in Natural Product Synthesis

Authors

Christian D.-T. Nielsen

Department of Chemistry, Imperial College London, Exhibition Road, London, SW7 2AZ, UK Email: a.c.spivey@imperial.ac.uk
Hossay Abas

Department of Chemistry, Imperial College London, Exhibition Road, London, SW7 2AZ, UK Email: a.c.spivey@imperial.ac.uk
Alan C. Spivey *

Department of Chemistry, Imperial College London, Exhibition Road, London, SW7 2AZ, UK Email: a.c.spivey@imperial.ac.uk

Abstract

All articles of this category

^‡ These authors contributed equally to this review.

Abstract

Herein presented is a review of the reactivity and synthetic utility of ortho-quinone methides and ortho-quinone methide imines. These versatile intermediates have received significant attention in the literature and new methods for their preparation and reaction as well as recent applications in total synthesis are discussed.

1 Introduction

2 Conjugate Addition Reactions

3 Concerted Cycloaddition Reactions

4 Stepwise Addition Reactions

5 Applications in Total Synthesis

6 Conclusion

Key words

ortho-quinone methide - ortho-quinone methide imine - total synthesis - review

Full Text

References

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