CC BY ND NC 4.0 · SynOpen 2018; 02(02): 0145-0149
DOI: 10.1055/s-0037-1609517
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Synthesis of Phthalimides: A New Entry via TBAI-Catalyzed Intramolecular Cyclization of 2-(Hydroxymethyl)benzamides

Kare Nagaraju
D-211, Discovery Laboratory, Organic & Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad-500007, India
Academy of Scientific and Innovative Research (AcSIR), New Delhi-110025, India   Email: prkgenius@iict.res.in
,
Nomula Rajesh
D-211, Discovery Laboratory, Organic & Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad-500007, India
,
Palakodety Radha Krishna*
D-211, Discovery Laboratory, Organic & Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad-500007, India
› Author Affiliations
K. N. and N. R. thank CSIR New Delhi for Research Fellowships. This research work was financially supported by the CSIR, New Delhi (BSC 0116).
Further Information

Publication History

Received: 21 March 2018

Accepted after revision: 19 April 2018

Publication Date:
16 May 2018 (online)

Communication No. IICT/Pubs./2018/080

Abstract

Herein we report an unprecedented metal-free TBAI/TBHP mediated C–N bond formation via intramolecular cyclization of 2-(hydroxymethyl)benzamides to furnish N-substituted phthalimides in excellent yields.

Supporting Information

 
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