Synfacts, Table of Contents Synfacts 2018; 14(05): 0455DOI: 10.1055/s-0037-1609498 Synthesis of Natural Products and Potential Drugs © Georg Thieme Verlag Stuttgart · New YorkSynthesis of GDC-0810Contributor(s): Philip KocienskiRecommend Article Abstract Buy ArticleKey words Key wordsGDC-0810 - selective estrogen receptor degrader - diastereoselective addition - Grignard reagent - Felkin–Anh model - asynchronous concerted E1 elimination - tetrasubstituted alkene Full Text