Thorac cardiovasc Surg 2017; 65(08): 634-638
DOI: 10.1055/s-0037-1606386
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Predictors of Surgical Outcome in Isolated Tricuspid Valve Endocarditis: Single Center Experience of 60 Patients

Mahmoud Singer1, Hesham Alkady1, Tarek Mohsen1, Amr Roushdy1, Alsayed Kamel Akl1, Marwa Mashaal2
  • 1Department of Cardiothoracic Surgery, Cairo University, Cairo, Almaneal, Egypt
  • 2Department of Cardiology, Cairo University, Cairo, Almaneal, Egypt
Further Information

Publication History

29 June 2017

31 July 2017

Publication Date:
18 September 2017 (eFirst)


Background Tricuspid valve (TV) endocarditis may be associated with serious complications, and 25% of patients require surgical intervention. However, indications and outcomes of surgery are not clearly identified. In this study, 60 patients are retrospectively reviewed to determine preoperative predictors of surgical outcome.

Patients and Methods Sixty patients with isolated TV endocarditis who underwent surgery in the period between January 2012 and December 2016 are reviewed retrospectively from the medical records of Cairo University Hospitals. Forty-two (70%) patients were males, and 18 (30%) were females with a mean age of 29.3 ± 10.6 years. Eleven patients had an underlying cardiac lesion, and 27 patients were intravenous (IV)-drug addicts.

Results TV repair could be done in nine (15%) patients, and the rest received TV replacement with biological valves. Twenty-four (40%) patients experienced postoperative complications. On multivariate analysis, a vegetation size >2.2 cm was a significant preoperative predictor for embolic complications and prolonged ventilation. In-hospital mortality occurred in 10 (16.67%) patients. Significant preoperative predictors of mortality were pulmonary embolization, congestive heart failure (HF), and the presence of pericardial effusion. During a mean follow-up period of 25 ± 12.6 months with echocardiography, two (4%) IV drug user patients developed recurrence of infection and needed reoperation.

Conclusion Surgery for tricuspid valve endocarditis (TVE) can be performed with good early and mid-term results. A large size of vegetations >2.2 cm is a significant risk factor for embolic complications. Preoperative predictors of in-hospital mortality according to our study are pulmonary embolization, congestive heart failure, and pericardial effusion.