Am J Perinatol 2018; 35(01): 055-058
DOI: 10.1055/s-0037-1605576
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Tale of Two Patent Ductus Arteriosus Severity Scores: Similarities and Differences

Daniel Fink
1   Department of Pediatric Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel
,
Afif El-Khuffash
2   Department of Neonatology, Rotunda Hospital, Rotunda, Dublin, Ireland
3   Department of Pediatrics, Royal College of Surgeons in Ireland, Dublin, Ireland
,
Patrick J. McNamara
4   Division of Neonatology, Hospital for Sick Children, Toronto, Ontario, Canada
5   Departments of Physiology and Pediatrics, University of Toronto, Toronto, Ontario, Canada
,
Itamar Nitzan
6   Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel
,
Cathy Hammerman
6   Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel
7   Faculty of Medicine, Hebrew University, Jerusalem, Israel
› Author Affiliations
Further Information

Publication History

18 May 2017

07 July 2017

Publication Date:
08 August 2017 (online)

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Abstract

Introduction Several echocardiographic scoring systems have been developed to assess the severity of patent ductus arteriosus (PDA) shunting in preterm infants.

Objective The objective of this study was to compare the ability of two different scoring systems to evaluate the hemodynamic significance of the PDA and to predict long-term PDA-associated morbidities.

Subjects El-Khuffash cohort (previously described) was derived from a multicenter, prospective, observational study conducted in tertiary neonatal intensive care units in Ireland, Canada, and Australia.

Results A total of 141 infants with a mean gestational age of 26 ± 1.4 weeks and a mean birth weight of 952 ± 235 g were evaluated on day 2 of life. The two scores were well correlated with each other and both scores positively predicted chronic lung disease/death in this population.

Conclusion There appears to be an overall stepwise progression in the incidence of poor outcome parameters from “closed” to “borderline” to “hemodynamically significant” PDA. Both the El-Khuffash and Shaare Zedek scores are predictive of PDA-associated morbidities.

Note

Daniel Fink and Afif El-Khuffash contributed equally to this study. All authors reviewed the article for important intellectual contents and approved the final version. All authors agree to be accountable for all aspects of the work. No honorarium, grant, or other form of payment was received to produce the article.


Funding

None.