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CC BY-NC-ND 4.0 · Journal of Child Science 2017; 07(01): e54-e59
DOI: 10.1055/s-0037-1603802
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Neonatal Sepsis: Clinical Considerations

S. Blatt
1   Neonatologie und Pädiatrische Intensivmedizin, Cnopf'sche Kinderklinik, Nürnberg, Germany
,
M. Schroth
1   Neonatologie und Pädiatrische Intensivmedizin, Cnopf'sche Kinderklinik, Nürnberg, Germany
› Author Affiliations
Further Information

Publication History

14 December 2016

20 December 2016

Publication Date:
26 July 2017 (online)

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Abstract

Unspecific symptoms and rapid development of sepsis up to septic shock from systemic inflammatory response syndrome (SIRS) are well-known, important issues in neonatology. A common cause is the infection by Streptococcus agalactiae (Group B Streptococcus [GBS]) or Escherichia coli, which contributes significantly to neonatal morbidity and mortality. Whereas early-onset sepsis is normally derived from mother during birth, late-onset sepsis can be transmitted by the environment. Management of neonatal sepsis includes the maintenance of cardiovascular and pulmonary function besides antibiotic therapy. Due to the fact that until today, there are no reliable screening tests for detecting early sepsis, clinical assessment is considered to be of utmost importance.

Keywords

neonatal sepsis - late-onset - early-onset - group B Streptococcus - diagnosis
 

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