CC BY ND NC 4.0 · SynOpen 2018; 02(01): 0058-0063
DOI: 10.1055/s-0036-1591931
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First Total Synthesis of Cryptopyranmoscatone A3 and Crypto­pyranmoscatone B4

A. Maheswara Reddy
Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India   Email: gowravaramsr@yahoo.com   Email: sabitha@iict.res.in
,
Gowravaram Sabitha*
Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India   Email: gowravaramsr@yahoo.com   Email: sabitha@iict.res.in
› Author Affiliations
The authors thank the Council of Scientific and Industrial Research (CSIR), New Delhi, India, for financial support as part of a five year programme under the title ORIGIN (CSC-0108). A.M. thanks the Council of Scientific and Industrial Research (CSIR), New Delhi, India, for financial assistance in the form of a Research Fellowship.
Further Information

Publication History

Received: 04 October 2017

Accepted after revision: 20 January 2018

Publication Date:
27 February 2018 (online)

Abstract

The first total synthesis of cryptopyranmoscatones A3 and B4 has been accomplished from d-ribose or but-3-ynol. The key steps involved in the synthesis are oxa-Michael addition, highly diastereo­selective Brown allylation, and ring closing metathesis (RCM) and cross metathesis (CM) reactions.

Supporting Information

 
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