CC BY ND NC 4.0 · SynOpen 2018; 02(02): 0128-0132
DOI: 10.1055/s-0036-1591573
paper
Copyright with the author

[4+3]-Annulation of 3-Cyano-4-aryl-2-iminochromenes with 1,2-Diaminobenzene: An Access to Novel Chromenobenzodiazepines

Mohini Mourya
a  Department of Chemistry, University of Rajasthan, JLN Marg, Jaipur-302004, India   Email: akb31377@gmail.com
,
Himanshu Sharma
a  Department of Chemistry, University of Rajasthan, JLN Marg, Jaipur-302004, India   Email: akb31377@gmail.com
,
Yogesh C. Joshi
a  Department of Chemistry, University of Rajasthan, JLN Marg, Jaipur-302004, India   Email: akb31377@gmail.com
,
a  Department of Chemistry, University of Rajasthan, JLN Marg, Jaipur-302004, India   Email: akb31377@gmail.com
b  Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi-221005, India
› Author Affiliations
A research grant from DST-SERB (YSS/2014/000957) and UGC (F.4–5/2006(BSR)), New Delhi is gratefully acknowledged.

Further Information

Publication History

Received: 26 February 2018

Accepted after revision: 05 April 2018

Publication Date:
08 May 2018 (online)

Abstract

3-Cyano-4-aryl-2-iminochromenes undergo [4+3]-annulation with 1,2-diaminobenzene under mild acidic conditions to generate novel chromenobenzodiazepines in good yields. The annulation reaction was also successful with 2-aminophenol and 2-aminothiophenol. The chromenobenzodiazepines could be conveniently reduced to the corresponding 4H-chromenobenzodiazepines under mild acidic conditions.

Supporting Information

 
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