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CC BY-ND-NC 4.0 · SynOpen 2017; 01(01): 0103-0116
DOI: 10.1055/s-0036-1588556
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The Synthesis of Single Enantiomers of α-Mycolic Acids of Mycobacterium­ tuberculosis and Related Organisms, with Alternative­ Cyclopropane Stereochemistries

Chioma Don Lawson
,
Max Maza-Iglesias
,
Muthana M. Sirhan
,
Jumaa R. Al Dulayymi
,
Mark S. Baird*
Further Information

Publication History

Received: 31 May 2017

Accepted after revision: 07 August 2017

Publication Date:
29 August 2017 (online)

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Abstract

We report the synthesis of three stereoisomers of a mycolic acid from Mycobacterium tuberculosis containing a di-cis-cyclopropane and of two stereoisomers of a mycolic acid containing a proximal trans-cyclopropane and a distal cis-cyclopropane.

Key words

mycolic acid - cis-cyclopropane - trans-cyclopropane - stereoisomers­

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1588556.
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