Synlett 2017; 28(06): 654-663
DOI: 10.1055/s-0036-1588402
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© Georg Thieme Verlag Stuttgart · New York

3-Acyltetramic Acids: A Decades-Long Approach to a Fascinating Natural Product Family

Markus Petermichl
Organisch-chemisches Laboratorium der Universität Bayreuth, Gebäude NW I, 95440 Bayreuth, Germany   Email: [email protected]
,
Rainer Schobert*
Organisch-chemisches Laboratorium der Universität Bayreuth, Gebäude NW I, 95440 Bayreuth, Germany   Email: [email protected]
› Author Affiliations
Further Information

Publication History

Received: 14 December 2016

Accepted after revision: 03 January 2016

Publication Date:
24 January 2017 (online)


Abstract

This account relates our quest for effective syntheses of 3-acyltetramic acids and also presents examples of our group’s increasing audacity to tackle the more intricate structural varieties of this compound class.

1 Introduction

2 A New Wittig-Based Access to Tetramic Acids

3 3-Acyltetramic Acids with Linear Side Chains

4 3-Decalinoyltetramic Acids

5 O- and N-Glycosylated 3-Acyltetramic Acids

6 Macrocyclic 3-Acyltetramic Acids

7 Miscellaneous Reactions

8 Whither to go from Here?

 
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