Semin Respir Crit Care Med 2016; 37(02): 267-276
DOI: 10.1055/s-0036-1578803
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Lung Malignancies in HIV Infection

Keith Sigel
1   Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
,
Robert Pitts
1   Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
,
Kristina Crothers
2   Department of Medicine, University of Washington, Seattle, Washington
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
14. März 2016 (online)

Preview

Abstract

Pulmonary malignancies are a major source of morbidity and mortality in HIV-infected persons. Non–AIDS-defining lung cancers (mostly non-small cell lung cancers) are now a leading cause of cancer death among HIV-infected persons. HIV-associated factors appear to affect the risk of lung cancer and may adversely impact cancer treatment and outcomes. HIV infection also may modify the potential harms and benefits of lung cancer screening with computed tomography. AIDS-defining lung malignancies include pulmonary Kaposi sarcoma and pulmonary lymphoma, both of which are less prevalent with widespread adoption of antiretroviral therapy.