J Knee Surg 2016; 29(07): 580-588
DOI: 10.1055/s-0035-1569479
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Knee Arthrodesis in Persistently Infected Total Knee Arthroplasty

Halil Ibrahim Balci
1   Department of Orthopedics and Traumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
,
Yavuz Saglam
2   Department of Orthopedics and Traumatology, Bahcelievler State Hospital, Istanbul, Turkey
,
Tuna Pehlivanoglu
1   Department of Orthopedics and Traumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
,
Cengiz Sen
1   Department of Orthopedics and Traumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
,
Levent Eralp
3   Department of Orthopedics and Traumatology, Memorial Sisli Hospital, Istanbul, Turkey
,
Mehmet Kocaoglu
3   Department of Orthopedics and Traumatology, Memorial Sisli Hospital, Istanbul, Turkey
› Author Affiliations
Further Information

Publication History

01 August 2015

20 October 2015

Publication Date:
18 December 2015 (online)

Abstract

The reported incidence of infection in total knee arthroplasty (TKA) varies from 0.5 to 15%. The most common indication for knee arthrodesis is persistent infection after repeated staged knee replacement. The purpose of this study is to investigate the success of fusion with monoplanar fixators and eradication rates of infection, and to evaluate the satisfaction of patients who underwent a last-resort TKA due to infection.

This is a retrospective review of infected knee arthroplasties that were treated with knee arthrodesis using unilateral external fixators at a single institution from 1999 through 2012. The patients' charts were analyzed for demographics, types of external fixators used, infection parameters, external fixator indexes, complications, positions of fusion, and leg length discrepancies (LLDs). Patients were called back to return for additional follow-up. A self-administered general health status questionnaire (SF-36) was assessed to evaluate life quality.

There were 14 women and 3 men with an average age of 67 ± 16.6 years. Antibiotic-loaded acrylic cements were used as a spacer for an average of 3.4 ± 1.2 months in all patients. Monoplanar type of external fixator was used in all 17 patients. Fusions were achieved in all but one patient. The mean duration of fusion was 6.8 ± 2.2 months and external fixator duration was 7.6 ± 2.4 months. Average LLD was 2.9 ± 1.7 cm. The mean coronal alignment of fusion was 6.8 degrees (± 3.3 degrees, range 4–15 degrees) valgus and mean flexion was 11.3 degrees (± 6.5 degrees, range 3–30 degrees). Compared with the healthy controls, the SF-36 scores were significantly lower in patients with knee arthrodesis (physical component score [PCS]-arthrodesis: 39.3 vs. PCS- healthy controls: 47.9, p < 0.05; mental component score [MCS]-arthrodesis: 38.6 versus MCS-healthy controls: 47.7, p < 0.05).

Use of monoplanar fixators for arthrodesis in infected TKA can achieve high fusion rates with the control of infection. If fusion can be achieved, the patient satisfaction is low with acceptable pain relief and functionality. We observed that monoplanar external fixators increased patients' comfort levels compared with circular external fixators. Further studies are needed to compare different arthrodesis modalities in patients with infected TKA.

 
  • References

  • 1 Bengtson S, Knutson K. The infected knee arthroplasty. A 6-year follow-up of 357 cases. Acta Orthop Scand 1991; 62 (4) 301-311
  • 2 Johnson DP, Bannister GC. The outcome of infected arthroplasty of the knee. J Bone Joint Surg Br 1986; 68 (2) 289-291
  • 3 Lee JK, Choi CH. Two-stage reimplantation in infected total knee arthroplasty using a re-sterilized tibial polyethylene insert and femoral component. J Arthroplasty 2012; 27 (9) 1701-1706.e1
  • 4 Oostenbroek HJ, van Roermund PM. Arthrodesis of the knee after an infected arthroplasty using the Ilizarov method. J Bone Joint Surg Br 2001; 83 (1) 50-54
  • 5 Galat DD, McGovern SC, Larson DR, Harrington JR, Hanssen AD, Clarke HD. Surgical treatment of early wound complications following primary total knee arthroplasty. J Bone Joint Surg Am 2009; 91 (1) 48-54
  • 6 Garvin KL, Konigsberg BS. Infection following total knee arthroplasty: prevention and management. J Bone Joint Surg Am 2011; 93 (12) 1167-1175
  • 7 Peersman G, Laskin R, Davis J, Peterson M. Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop Relat Res 2001; (392) 15-23
  • 8 Eralp L, Kocaoğlu M, Tuncay I, Bilen FE, Samir SE. Knee arthrodesis using a unilateral external fixator for the treatment of infectious sequelae. Acta Orthop Traumatol Turc 2008; 42 (2) 84-89
  • 9 Hanssen AD, Trousdale RT, Osmon DR. Patient outcome with reinfection following reimplantation for the infected total knee arthroplasty. Clin Orthop Relat Res 1995; (321) 55-67
  • 10 Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am 2007; 89 (4) 780-785
  • 11 Raskolnikov D, Slover JD, Egol KA. The use of a multiplanar, multi-axis external fixator to achieve knee arthrodesis in a worst case scenario: a case series. Iowa Orthop J 2013; 33: 19-24
  • 12 Conway JD, Mont MA, Bezwada HP. Arthrodesis of the knee. J Bone Joint Surg Am 2004; 86-A (4) 835-848
  • 13 Corona PS, Hernandez A, Reverte-Vinaixa MM, Amat C, Flores X. Outcome after knee arthrodesis for failed septic total knee replacement using a monolateral external fixator. J Orthop Surg (Hong Kong) 2013; 21 (3) 275-280
  • 14 MacDonald JH, Agarwal S, Lorei MP, Johanson NA, Freiberg AA. Knee arthrodesis. J Am Acad Orthop Surg 2006; 14 (3) 154-163
  • 15 Vlasak R, Gearen PF, Petty W. Knee arthrodesis in the treatment of failed total knee replacement. Clin Orthop Relat Res 1995; (321) 138-144
  • 16 Woods GW, Lionberger DR, Tullos HS. Failed total knee arthroplasty. Revision and arthrodesis for infection and noninfectious complications. Clin Orthop Relat Res 1983; (173) 184-190
  • 17 Puranen J, Kortelainen P, Jalovaara P. Arthrodesis of the knee with intramedullary nail fixation. J Bone Joint Surg Am 1990; 72 (3) 433-442
  • 18 Wilde AH, Stearns KL. Intramedullary fixation for arthrodesis of the knee after infected total knee arthroplasty. Clin Orthop Relat Res 1989; (248) 87-92
  • 19 Donley BG, Matthews LS, Kaufer H. Arthrodesis of the knee with an intramedullary nail. J Bone Joint Surg Am 1991; 73 (6) 907-913
  • 20 Ilizarov GA, Kaplunov AG, Degtiarev VE, Lediaev VI. Treatment of pseudarthroses and ununited fractures, complicated by purulent infection, by the method of compression-distraction osteosynthesis. Ortop Travmatol Protez 1972; 33 (11) 10-14
  • 21 Manzotti A, Pullen C, Deromedis B, Catagni MA. Knee arthrodesis after infected total knee arthroplasty using the Ilizarov method. Clin Orthop Relat Res 2001; (389) 143-149
  • 22 Benson ER, Resine ST, Lewis CG. Functional outcome of arthrodesis for failed total knee arthroplasty. Orthopedics 1998; 21 (8) 875-879
  • 23 Cierny III G, Mader JT, Penninck JJ. A clinical staging system for adult osteomyelitis. Clin Orthop Relat Res 2003; (414) 7-24
  • 24 Paley D. Problems, obstacles, and complications of limb lengthening by the Ilizarov technique. Clin Orthop Relat Res 1990; (250) 81-104
  • 25 Demiral Y, Ergor G, Unal B , et al. Normative data and discriminative properties of short form 36 (SF-36) in Turkish urban population. BMC Public Health 2006; 6: 247
  • 26 Nelson CL, Evarts CM. Arthroplasty and arthrodesis of the knee joint. Orthop Clin North Am 1971; 2 (1) 245-264
  • 27 Isiklar ZU, Landon GC, Tullos HS. Amputation after failed total knee arthroplasty. Clin Orthop Relat Res 1994; (299) 173-178
  • 28 Gunes T, Sen C, Erdem M. Knee arthrodesis using circular external fixator in the treatment of infected knee prosthesis: case report. Knee Surg Sports Traumatol Arthrosc 2005; 13 (4) 329-334
  • 29 McQueen DA, Cooke FW, Hahn DL. Knee arthrodesis with the Wichita Fusion Nail: an outcome comparison. Clin Orthop Relat Res 2006; 446 (446) 132-139
  • 30 Waldman BJ, Mont MA, Payman KR , et al. Infected total knee arthroplasty treated with arthrodesis using a modular nail. Clin Orthop Relat Res 1999; (367) 230-237
  • 31 Garberina MJ, Fitch RD, Hoffmann ED, Hardaker WT, Vail TP, Scully SP. Knee arthrodesis with circular external fixation. Clin Orthop Relat Res 2001; (382) 168-178
  • 32 Lucas DB, Murray WR. Arthrodesis of the knee by double-plating. . JBJS 1961; 43 (6) 795-808
  • 33 Nichols SJ, Landon GC, Tullos HS. Arthrodesis with dual plates after failed total knee arthroplasty. J Bone Joint Surg Am 1991; 73 (7) 1020-1024
  • 34 Kuo AC, Meehan JP, Lee M. Knee fusion using dual platings with the locking compression plate. J Arthroplasty 2005; 20 (6) 772-776
  • 35 Mabry TM, Jacofsky DJ, Haidukewych GJ, Hanssen AD. Comparison of intramedullary nailing and external fixation knee arthrodesis for the infected knee replacement. Clin Orthop Relat Res 2007; 464 (464) 11-15
  • 36 Knutson K, Bodelind B, Lidgren L. Stability of external fixators used for knee arthrodesis after failed knee arthroplasty. Clin Orthop Relat Res 1984; (186) 90-95
  • 37 Parratte S, Madougou S, Villaba M, Stein A, Rochwerger A, Curvale G. Knee arthrodesis with a double mono-bar external fixators to salvage infected knee arthroplasty: retrospective analysis of 18 knees with mean seven-year follow-up [in French]. Rev Chir Orthop Repar Appar Mot 2007; 93 (4) 373-380
  • 38 Riouallon G, Molina V, Mansour C, Court C, Nordin JY. An original knee arthrodesis technique combining external fixator with Steinman pins direct fixation. Orthop Traumatol Surg Res 2009; 95 (4) 272-277
  • 39 Flynn JM. Orthopaedic Knowledge Update 10. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2011
  • 40 Crockarell Jr JR, Mihalko MJ. Knee arthrodesis using an intramedullary nail. J Arthroplasty 2005; 20 (6) 703-708