Thorac Cardiovasc Surg 2014; 62 - v15
DOI: 10.1055/s-0034-1393991

Timing of repair and long-term perspectives in Fallot repair: a multistate-analysis of 469 patients aged ≤ 65 years

A. Horke 1, D. Bobylev 1, K. Beck 2, L. Meschenmoser 1, M. Westhoff-Bleck 2, U. Grosser 2, Ph. Beerbaum 2, H. Hecker 1, D. Boethig 1, 2
  • 1Klinik für Pädiatrische Kardiologie und Intensivmedizin
  • 2Klinik für Herz-, Thorax-, Transplantations- und Gefäßchirurgie, Medizinische Hochschule Hannover, Hannover

Background: Recently Fallot repair within the first life year has been advocated over delayed repair; evidence from long-term FU data is sparse.

Methods: We compared numbers of re-operations and survival rate in a single-center retrospective study of 469 subjects after Fallot repair, applying multi state analysis (R-package mstate). Three age groups were formed: age at repair of <1 y (n=124), 1-5 y (148), > 5 y (109).

Results: In the mentioned 3 age groups, current mean patient age (range/median) were 0 to 36/11.5; 1.1 to 38/17.1; 5.1 to 64/24.0. Male/female ratio of the total population: 0.56. Numbers of palliations/Redos/deaths were 11/55/20; 28/63/15; 65/47/17, respectively. The figure shows the fraction of patients in any status during their observed life time, stratified by age at repair.

Conclusions: Considering survival and the numbers of reoperations, the benefit of TOF repair in the first year of life instead of repair in preschool age is not evident in our cohort.