Planta Med 2014; 80 - PPL16
DOI: 10.1055/s-0034-1382652

NMR-based metabolomics for chemotaxonomic characterization and authentification of Astragalus species

J Zhao 1, E Bedir 4, M Wang 1, B Avula 1, YH Wang 1, S Sagi 1, V Raman 1, IA Khan 1, 2, 3
  • 1National Center for Natural Products Research
  • 2Department of Pharmacognosy, School of Pharmacy, University of Mississippi, University, MS 38677, USA
  • 3Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
  • 4Department of Bioengineering, Ege University, Bornova 35100, Izmir, Turkey

Astragalus is the largest genus of flowering plants in the world, with more than 2200 species which are widely distributed throughout the temperate region of the world. Many of the species are of highly economic and ecological importance, used as food, forage, industrial raw materials, and herbal medicines. Some species are poisonous. The metabolomic analysis of Astragalus species was performed by using NMR combining chemometric methods. The chemotaxonomic characteristic fingerprinting and metabolite profile of Astragalus propinquus, an important medicinal herb used in TCM for centuries, were investigated to facilitate the authentification and quality control of plant materials.