Synthesis of Dual Orexin Receptor Antagonist MK-6096

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Synfacts 2015; 11(2): 0113
DOI: 10.1055/s-0034-1379790

Synthesis of Natural Products and Potential Drugs

Contributor(s):

Philip Kocienski

Further Information

Publication Date:
19 January 2015 (online)

MK-6096 - orexin antagonists - amide bond formation - 1-propylphosphonic anhydride - enzymatic transamination - Mukaiyama directed aldol reaction