J Knee Surg 2015; 28(01): 083-088
DOI: 10.1055/s-0034-1371769
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Adverse Effect of Femoral Nerve Blockade on Quadriceps Strength and Function after ACL Reconstruction

Aaron Krych
1   Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota
,
Grigoriy Arutyunyan
1   Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota
,
Scott Kuzma
1   Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota
,
Bruce Levy
1   Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota
,
Diane Dahm
1   Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota
,
Michael Stuart
1   Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota
› Author Affiliations
Further Information

Publication History

07 May 2013

18 January 2014

Publication Date:
12 March 2014 (online)

Abstract

The purpose of this study was to determine if quadriceps strength and functional outcomes were similar at 6 months following anterior cruciate ligament [ACL] reconstruction in patients receiving a continuous 48-hour femoral nerve blockade for postoperative analgesia (FNB group) versus patients with no FNB (control group). A retrospective cohort was designed including athletes who underwent primary ACL reconstruction with patellar tendon autograft between 2005 and 2010 at our institution with identical rehabilitation protocols. The FNB group included 96 patients with an average age of 21 years and the control group included 100 patients with an average age of 20 years. At 6 months following ACL reconstruction, isokinetic strength (slow and fast activation) and functional tests including vertical jump, single hop, triple hop, and return to sport were analyzed with an α value < 0.05 as significant. Multivariate regression models were used to compare these outcomes between the FNB and control groups after adjusting for gender and competitive athlete status. At 6 months, fast extension isokinetic strength was inferior in the FNB group (78 vs. 85%; p < 0.01). After adjusting for gender and competitive athlete status, fast (p = 0.002) and slow extension strength (p = 0.01), vertical jump (p = 0.03) and single jump (p = 0.02) were also inferior in the FNB group. There were no significant differences in full return to sport between the two groups (86% at 7.5 months in the FNB group vs. 93% at 7.3 months in the control group). In this retrospective comparative study, the hypothesis that patients treated with continuous FNB for postoperative analgesia following ACL reconstruction with patellar tendon autograft will have inferior knee extension (quadriceps) strength and function at 6 months follow-up was affirmed. However, no differences were observed in return to sport, bringing into question whether these statistical differences translate into meaningful clinical consequences after ACL reconstruction. The level of evidence was level III, retrospective case–control series.

 
  • References

  • 1 Tierney GS, Wright RW, Smith JP, Fischer DA. Anterior cruciate ligament reconstruction as an outpatient procedure. Am J Sports Med 1995; 23 (6) 755-756
  • 2 Dauri M, Sidiropoulou T, Fabbi E , et al. Efficacy of continuous femoral nerve block with stimulating catheters versus nonstimulating catheters for anterior cruciate ligament reconstruction. Reg Anesth Pain Med 2007; 32 (4) 282-287
  • 3 Harris N, Bickerstaff D, Farquharson D , et al. Postoperative analgesia following anterior cruciate ligament reconstruction: a controlled study using femoral nerve regional anaesthesia. Knee 1997; 4: 197-201
  • 4 Iskandar H, Benard A, Ruel-Raymond J, Cochard G, Manaud B. Femoral block provides superior analgesia compared with intra-articular ropivacaine after anterior cruciate ligament reconstruction. Reg Anesth Pain Med 2003; 28 (1) 29-32
  • 5 Mayr HO, Entholzner E, Hube R, Hein W, Weig TG. Pre- versus postoperative intraarticular application of local anesthetics and opioids versus femoral nerve block in anterior cruciate ligament repair. Arch Orthop Trauma Surg 2007; 127 (4) 241-244
  • 6 Mulroy MF, Larkin KL, Batra MS, Hodgson PS, Owens BD. Femoral nerve block with 0.25% or 0.5% bupivacaine improves postoperative analgesia following outpatient arthroscopic anterior cruciate ligament repair. Reg Anesth Pain Med 2001; 26 (1) 24-29
  • 7 Williams BA, Kentor ML, Vogt MT , et al. Reduction of verbal pain scores after anterior cruciate ligament reconstruction with 2-day continuous femoral nerve block: a randomized clinical trial. Anesthesiology 2006; 104 (2) 315-327
  • 8 Frost S, Grossfeld S, Kirkley A, Litchfield B, Fowler P, Amendola A. The efficacy of femoral nerve block in pain reduction for outpatient hamstring anterior cruciate ligament reconstruction: a double-blind, prospective, randomized trial. Arthroscopy 2000; 16 (3) 243-248
  • 9 Mall NA, Wright RW. Femoral nerve block use in anterior cruciate ligament reconstruction surgery. Arthroscopy 2010; 26 (3) 404-416
  • 10 Matava MJ, Prickett WD, Khodamoradi S, Abe S, Garbutt J. Femoral nerve blockade as a preemptive anesthetic in patients undergoing anterior cruciate ligament reconstruction: a prospective, randomized, double-blinded, placebo-controlled study. Am J Sports Med 2009; 37 (1) 78-86
  • 11 Mehdi SA, Dalton DJN, Sivarajan V, Leach WJ. BTB ACL reconstruction: femoral nerve block has no advantage over intraarticular local anaesthetic infiltration. Knee Surg Sports Traumatol Arthrosc 2004; 12 (3) 180-183
  • 12 Schwarz SK, Franciosi LG, Ries CR , et al. Addition of femoral 3-in-1 blockade to intra-articular ropivacaine 0.2% does not reduce analgesic requirements following arthroscopic knee surgery. Can J Anaesth 1999; 46 (8) 741-747
  • 13 Woods GW, O'Connor DP, Calder CT. Continuous femoral nerve block versus intra-articular injection for pain control after anterior cruciate ligament reconstruction. Am J Sports Med 2006; 34 (8) 1328-1333
  • 14 Frerk CM. Palsy after femoral nerve block. Anaesthesia 1988; 43 (2) 167-168
  • 15 Lynch J. Prolonged motor weakness after femoral nerve block with bupivacaine 0.5%. Anaesthesia 1990; 45 (5) 421
  • 16 Wiegel M, Gottschaldt U, Hennebach R, Hirschberg T, Reske A. Complications and adverse effects associated with continuous peripheral nerve blocks in orthopedic patients. Anesth Analg 2007; 104 (6) 1578-1582
  • 17 Albrecht E, Niederhauser J, Gronchi F , et al. Transient femoral neuropathy after knee ligament reconstruction and nerve stimulator-guided continuous femoral nerve block: a case series. Anaesthesia 2011; 66 (9) 850-851
  • 18 Krych AJ, Horlocker TT, Hebl JR, Pagnano MW. Contemporary pain management strategies for minimally invasive total knee arthroplasty. Instr Course Lect 2010; 59: 99-109
  • 19 Salinas FV, Neal JM, Sueda LA, Kopacz DJ, Liu SS. Prospective comparison of continuous femoral nerve block with nonstimulating catheter placement versus stimulating catheter-guided perineural placement in volunteers. Reg Anesth Pain Med 2004; 29 (3) 212-220
  • 20 Ilfeld BM. Continuous peripheral nerve blocks: a review of the published evidence. Anesth Analg 2011; 113 (4) 904-925
  • 21 Dauty M, Tortellier L, Rochcongar P. Isokinetic and anterior cruciate ligament reconstruction with hamstrings or patella tendon graft: analysis of literature. Int J Sports Med 2005; 26 (7) 599-606
  • 22 Kvist J. Rehabilitation following anterior cruciate ligament injury: current recommendations for sports participation. Sports Med 2004; 34 (4) 269-280
  • 23 Augustsson J, Thomeé R, Karlsson J. Ability of a new hop test to determine functional deficits after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2004; 12 (5) 350-356
  • 24 Xergia SA, McClelland JA, Kvist J, Vasiliadis HS, Georgoulis AD. The influence of graft choice on isokinetic muscle strength 4-24 months after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2011; 19 (5) 768-780
  • 25 Carter TR, Edinger S. Isokinetic evaluation of anterior cruciate ligament reconstruction: hamstring versus patellar tendon. Arthroscopy 1999; 15 (2) 169-172
  • 26 Maletis GB, Cameron SL, Tengan JJ, Burchette RJ. A prospective randomized study of anterior cruciate ligament reconstruction: a comparison of patellar tendon and quadruple-strand semitendinosus/gracilis tendons fixed with bioabsorbable interference screws. Am J Sports Med 2007; 35 (3) 384-394
  • 27 Aune AK, Holm I, Risberg MA, Jensen HK, Steen H. Four-strand hamstring tendon autograft compared with patellar tendon-bone autograft for anterior cruciate ligament reconstruction. A randomized study with two-year follow-up. Am J Sports Med 2001; 29 (6) 722-728
  • 28 Arciero RA, Scoville CR, Hayda RA, Snyder RJ. The effect of tourniquet use in anterior cruciate ligament reconstruction. A prospective, randomized study. Am J Sports Med 1996; 24 (6) 758-764
  • 29 Eitzen I, Holm I, Risberg MA. Preoperative quadriceps strength is a significant predictor of knee function two years after anterior cruciate ligament reconstruction. Br J Sports Med 2009; 43 (5) 371-376
  • 30 Ilfeld BM, Shuster JJ, Theriaque DW , et al. Long-term pain, stiffness, and functional disability after total knee arthroplasty with and without an extended ambulatory continuous femoral nerve block: a prospective, 1-year follow-up of a multicenter, randomized, triple-masked, placebo-controlled trial. Reg Anesth Pain Med 2011; 36 (2) 116-120
  • 31 Paauwe JJ, Thomassen BJ, Weterings J, van Rossum E, Ausems ME. Femoral nerve block using ropivacaine 0.025%, 0.05% and 0.1%: effects on the rehabilitation programme following total knee arthroplasty: a pilot study. Anaesthesia 2008; 63 (9) 948-953
  • 32 Sharma S, Iorio R, Specht LM, Davies-Lepie S, Healy WL. Complications of femoral nerve block for total knee arthroplasty. Clin Orthop Relat Res 2010; 468 (1) 135-140
  • 33 Auroy Y, Benhamou D, Bargues L , et al. Major complications of regional anesthesia in France: The SOS Regional Anesthesia Hotline Service. Anesthesiology 2002; 97 (5) 1274-1280
  • 34 Cuvillon P, Ripart J, Lalourcey L , et al. The continuous femoral nerve block catheter for postoperative analgesia: bacterial colonization, infectious rate and adverse effects. Anesth Analg 2001; 93 (4) 1045-1049
  • 35 Watts SA, Sharma DJ. Long-term neurological complications associated with surgery and peripheral nerve blockade: outcomes after 1065 consecutive blocks. Anaesth Intensive Care 2007; 35 (1) 24-31
  • 36 Schafhalter-Zoppoth I, Zeitz ID, Gray AT. Inadvertent femoral nerve impalement and intraneural injection visualized by ultrasound. Anesth Analg 2004; 99 (2) 627-628