Amer J Perinatol 2013; 30(01): 001-004
DOI: 10.1055/s-0032-1322511
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Role of Massive Transfusion Protocols in Obstetrics

Luis D. Pacheco
1  Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
2  Division of Surgical Critical Care, Department of Anesthesiology, The University of Texas Medical Branch, Galveston, Texas
,
George R. Saade
1  Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
,
Maged M. Costantine
1  Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
,
Steven L. Clark
3  Women and Newborns Clinical Program, Hospital Corporation of America, Salt Lake City, Utah
,
Gary D.V. Hankins
1  Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas
› Author Affiliations
Further Information

Publication History

30 January 2012

16 March 2012

Publication Date:
26 July 2012 (eFirst)

Abstract

Obstetric hemorrhage is a leading cause of maternal mortality worldwide. New concepts involving the pathophysiology of hemorrhage have been described and include early activation of both the protein C and fibrinolytic pathways. New tendencies in hemorrhage treatment include the use of hemostatic resuscitation. Massive transfusion protocols involve the early utilization of blood products and limit the traditional approach of early massive crystalloid based resuscitation. The evidence behind hemostatic resuscitation is still limited.