DMW - Deutsche Medizinische Wochenschrift, Inhaltsverzeichnis Dtsch Med Wochenschr 2012; 137(40): 1998-2001DOI: 10.1055/s-0032-1305272 Endokrinologie und Diabetologie | Commentary Diabetologie, Nephrologie © Georg Thieme Verlag KG Stuttgart · New YorkDiabetes und NiereDiabetes and the kidneys B. Hohenstein 1 Medizinische Klinik 3, Bereich Nephrologie, Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden , C. Hugo 1 Medizinische Klinik 3, Bereich Nephrologie, Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden › InstitutsangabenArtikel empfehlen Abstract Artikel einzeln kaufenSchlüsselwörter Schlüsselwörterdiabetische Nephropathie - antidiabetische Therapie - Blutdrucksenkung - duale Renin-Angiotensin-Hemmung Keywords Keywordsdiabetic nephropathy - glucose control - blood pressure control - dual renin-angiotensin inhibition Volltext Referenzen Literatur 1 Bailey CJ, Gross JL, Pieters A et al. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin. Lancet 2010; 375: 2223-2233 2 Bilous R, Chaturvedi N, Sjolie AK et al. Effect of candesartan on microalbuminuria and albumin excretion rate in diabetes. Ann Intern Med 2009; 151: 11-20, W3-4 3 Bonegio R, Susztak K. Notch signaling in diabetic nephropathy. Exp Cell Res 2012; 318: 986-992 4 de Boer IH, Sun W, Cleary PA et al. Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes. N Engl J Med 2011; 365: 2366-2376 5 Fioretto P, Steffes MW, Sutherland DE et al. Reversal of lesions of diabetic nephropathy after pancreas transplantation. N Engl J Med 1998; 339: 69-75 6 Fiorina P, Folli F, Zerbini G et al. Islet transplantation is associated with improvement of renal function among uremic patients with type I diabetes mellitus and kidney transplants. J Am Soc Nephrol 2003; 14: 2150-2158 7 Godel M, Hartleben B, Herbach N et al. Role of Mtor in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest 2011; 121: 2197-2209 8 Haller H, Ito S, Izzo Jr JL et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med 2011; 364: 907-917 9 Ismail-Beigi F, Craven TE, O’Connor PJ et al. Combined intensive blood pressure and glycemic control does not produce an additive benefit on microvascular outcomes in type 2 diabetic patients. Kidney Int 2012; 81: 586-594 10 Levey AS, Cattran D, Friedman A et al. Proteinuria as a surrogate outcome in Ckd: Report of a Scientific Workshop Sponsored by the National Kidney Foundation and the US Food and Drug Administration. Am J Kidney Dis 2009; 54: 205-226 11 Ludwig B, Ludwig S, Steffen A et al. Islet versus pancreas transplantation in type 1 diabetes: competitive or complementary?. Curr Diab Rep 2010; 10: 506-511 12 Ludwig B, Rotem A, Schmid J et al. Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist. Proc Natl Acad Sci U S A 2012; 109: 5022-5027 13 Parving HH, Brenner BM, McMurray JJ et al. Baseline characteristics in the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (Altitude). J Renin Angiotensin Aldosterone Syst 2012; Feb 14. [Epub ahead of print] 14 Patel A, MacMahon S, Chalmers J et al. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the Advance Trial). Lancet 2007; 370: 829-840 15 Pergola PE, Raskin P, Toto RD et al. Bardoxolone methyl and kidney function in Ckd with type 2 diabetes. N Engl J Med 2011; 365; 327-336 16 Pohl MA, Blumenthal S, Cordonnier DJ et al. Independent and additive impact of blood pressure control and angiotensin II receptor blockade on renal outcomes in the Irbesartan Diabetic Nephropathy Trial. J Am Soc Nephrol 2005; 16: 3027-3037 17 Schmieder RE, Klingbeil AU, Fleischmann EH et al. Additional antiproteinuric effect of ultrahigh dose candesartan. J Am Soc Nephrol 2005; 16: 3038-3045 18 Vogt L, Waanders F, Boomsma F et al. Effects of dietary sodium and hydrochlorothiazide on the antiproteinuric efficacy of losartan. J Am Soc Nephrol 2008; 19: 999-1007 19 Wittmann S, Daniel C, Stief A et al. Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat. Transplantation 2009; 87: 1290-1299 20 Yusuf S, Teo KK, Pogue J et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 2008; 358: 1547-1559