Synthesis of Coumarins and Neoflavones
through Zinc Chloride Catalyzed Hydroarylation of Acetylenic Esters
with Phenols

Raquel A. C. Leão; Paula de F. de Moraes; Marcella C. B. C. Pedro; Paulo R. R. Costa

doi:10.1055/s-0031-1289576

PAPER

Synthesis of Coumarins and Neoflavones through Zinc Chloride Catalyzed Hydroarylation of Acetylenic Esters with Phenols

Raquel A. C. Leão, Paula de F. de Moraes, Marcella C. B. C. Pedro, Paulo R. R. Costa*
Laboratório de Química Bioorgânica (LQB), Núcleo de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Bloco H, Ilha da Cidade Universitária, 21941-590, Rio de Janeiro, RJ, Brazil
Fax: +55(21)25626793; e-Mail: prrcosta2011@gmail.com;

Abstract

Alle Artikel dieser Rubrik

Abstract

Acetylenic esters react with oxygenated phenols under solvent-free conditions in the presence of only 5 mol% of zinc chloride as a catalyst to give coumarins and neoflavones in reasonable-to-good yields.

Key words

phenols - catalysis - arylations - heterocycles - alkynes - esters

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References

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