Synfacts 2011(11): 1233-1233  
DOI: 10.1055/s-0031-1289200
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Oxidation of Silyl Enol Ethers with Metal Nitrites

Contributor(s): Paul Knochel, Thomas Kunz
M. Baidya, H. Yamamoto*
The University of Chicago, USA
Further Information

Publication History

Publication Date:
19 October 2011 (online)

Significance

The authors disclose an efficient and straightforward protocol for the preparation of a new nitroso reagent. These are used in oxidation reactions of silyl enol ethers affording keto oximes in high yield. The oxidizing agent is triisopropyl ­silyl nitrite which is generated in situ from silver ­nitrite and triisopropylsilyl chloride.