Pharmacopsychiatry 2012; 45(01): 28-30
DOI: 10.1055/s-0031-1286344
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Interferon-Induced Obsessive-Compulsive Symptoms in Malignant Melanoma

P. Mavrogiorgou
1  Department of Psychiatry, Ruhr University Bochum, LWL-University Hospital, Bochum, Germany
,
G. Juckel
1  Department of Psychiatry, Ruhr University Bochum, LWL-University Hospital, Bochum, Germany
› Author Affiliations
Further Information

Publication History

received 16 May 2011
revised 12 June 2011

accepted 26 July 2011

Publication Date:
11 October 2011 (online)

Abstract

Immunotherapy with alpha-interferon (IFN-α) is currently used as adjuvant treatment in patients with malignant melanoma. Psychiatric side effects such depression, mania or psychosis during treatment with IFN-α have been well documented in the literature. In comparison, however, data on interferon-induced obsessive-compulsive disorder are rare. We report here the case of a 23-year-old woman who developed obsessive-compulsive symptoms for the first time during interferon therapy after excision of a malignant melanoma.