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DOI: 10.1055/s-0031-1284005
Metastasiertes apokrines Adenokarzinom des Penis: zytostatische Therapie
Metastatic Apocrine Adenocarcinoma of the Penis: Cytostatic TherapyPublication History
Publication Date:
25 May 2012 (online)

Zusammenfassung
Das metastasierte apokrine Schweißdrüsenkarzinom im Genitalbereich stellt eine Seltenheit dar. Eine zytostatische Behandlung mit MTX und Bleomycin wurde empirisch durchgeführt und zeigte keine zufriedenstellende Wirksamkeit. Die Umstellung des chemotherapeutischen Regimes auf einen Thyrosinkinaseinhibitor (Sunitinib) zeigte einen bildmorphologisch und klinisch nachgewiesenen Erfolg im Sinne einer deutlichen Verlangsamung der vorher raschen Progredienz der Erkrankung.
Abstract
Metastatic carcinoma of the genital apocrine sweat glands is a rare clinical entity. A cytostatic treatment with MTX and bleomycin was performed empirically but did not show any satisfactory efficacy. The conversion of the chemotherapeutic regime to a tyrosine kinase inhibitor (sunitinib) showed a morphologically visible and clinically proven success in terms of a significant slowing down of the previous rapid progression of the disease.
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