Neuropediatrics 2011; 42(3): 122-123
DOI: 10.1055/s-0031-1283112
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

Prenatal MR Diffusion Tractography in a Fetus with Complete Corpus Callosum Agenesis

A. Meoded
1   Division of Pediatric Radiology, Russell H., Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USA
,
A. Poretti
1   Division of Pediatric Radiology, Russell H., Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USA
,
A. Tekes
1   Division of Pediatric Radiology, Russell H., Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USA
,
A. Flammang
2   Center for Applied Medical Imaging, Siemens Corporation, Baltimore, MD, USA
,
S. Pryde
1   Division of Pediatric Radiology, Russell H., Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USA
,
T.A.G.M. Huisman
1   Division of Pediatric Radiology, Russell H., Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USA
› Author Affiliations
Further Information

Publication History

received 11 April 2011

accepted 09 June 2011

Publication Date:
07 July 2011 (online)

Abstract

Diffusion tensor imaging (DTI) in combination with 3D-tractography reconstructions allows studying the neuro-architecture of complex brain malformations in vivo. Prenatal, in utero DTI has been limited by long acquisition times, poor signal to noise ratio and multiple artifacts. Recent developments in hard- and software allow collection of high quality DTI data sets in utero. We report on the DTI and tractography data of a fetus with a corpus callosum agenesis. Our case shows that nowadays the neuro-architecture of the fetal brain can be studied in excellent detail. Prenatal DTI and tractography may help to improve our understanding of complex brain malformations.

 
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