Abstract
Diffusion tensor imaging (DTI) in combination with 3D-tractography reconstructions
allows studying the neuro-architecture of complex brain malformations in vivo. Prenatal,
in utero DTI has been limited by long acquisition times, poor signal to noise ratio
and multiple artifacts. Recent developments in hard- and software allow collection
of high quality DTI data sets in utero. We report on the DTI and tractography data
of a fetus with a corpus callosum agenesis. Our case shows that nowadays the neuro-architecture
of the fetal brain can be studied in excellent detail. Prenatal DTI and tractography
may help to improve our understanding of complex brain malformations.
Key words
corpus callosum agenesis - fetal MRI - diffusion tensor imaging
