Semin Respir Crit Care Med 2011; 32(3): 328-334
DOI: 10.1055/s-0031-1279829
© Thieme Medical Publishers

Pulmonary-Renal Syndrome with a Focus on Anti-GBM Disease

Jan-Stephan F. Sanders1 , Abraham Rutgers2 , Coen A. Stegeman1 , Cees G.M. Kallenberg2
  • 1Department of Nephrology, University Medical Center Groningen (UMCG), University of Groningen, The Netherlands
  • 2Department of Rheumatology and Clinical Immunology, University Medical Center Groningen (UMCG), University of Groningen, The Netherlands
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Publikationsverlauf

Publikationsdatum:
14. Juni 2011 (online)

ABSTRACT

Pulmonary-renal syndrome is a potentially life-threatening combination of pulmonary hemorrhage and acute renal failure. Several pathological entities can cause this syndrome. This review discusses the diagnostic strategy required to initiate appropriate therapy. Rapid serological testing and appropriate interpretation can be of great additive diagnostic value. Also discussed are the pathogenesis, therapy, and outcome of anti–glomerular basement membrane disease, one of the pathological entities that can cause pulmonary-renal syndrome.

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Jan-Stephan F SandersM.D. Ph.D. 

Department of Nephrology, University Medical Center Groningen (UMCG), University of Groningen

P.O. Box 30.001, 9700 RB Groningen, The Netherlands

eMail: j.sanders@int.umcg.nl