J Reconstr Microsurg 2011; 27(3): 157-162
DOI: 10.1055/s-0030-1268855
© Thieme Medical Publishers

Risk Factors and Therapeutic Strategy after Failure of Free Flap Coverage for Lower-Limb Defects

Pierre Perrot1 , 2 , Anne-Laure Bouffaut1 , Christophe Perret3 , Jérôme Connault4 , Franck Duteille1 , 2
  • 1Service de chirurgie plastique et reconstructrice–Centre des brûlés, Hôpital Jean Monnet, CHU de Nantes, France
  • 2Inserm U957, Laboratoire de physiopathologie de la résorption osseuse, Université de Nantes, France
  • 3Service de radiologie, Hôpital Hôtel Dieu, CHU de Nantes, France
  • 4Service de médecine interne, Hôpital Hôtel Dieu, CHU de Nantes, Nantes, France
Further Information

Publication History

Publication Date:
23 November 2010 (online)


From 2004 to 2007, 148 limb free flaps were performed in a series of 138 patients at the University Hospital in Nantes, France. Flaps were successful in 127 instances (rate: 86%; group A) and failed in 21 (group B). An analysis of the various factors (pre-, intra-, and postoperative) in both groups that may have influenced the outcome of surgery identified the following: operating time, cold ischemia time, and the interval before reoperation. This report is based on our experience in managing 21 free flap failures during reconstructive surgery of the limbs. The causes of failure were analyzed, and possible therapeutic strategies defined (i.e., a second free flap procedure, a pedicle flap, coverage with artificial dermis, or amputation). In our opinion, careful analysis of the causes of flap failure is essential to an appropriate choice of subsequent therapeutic strategy.


Pierre Perrot, M.D. , Ph.D. 

Service de chirurgie plastique et reconstructrice–Centre des brûlés

Hôpital Jean Monnet, CHU de Nantes, 44093 Nantes Cedex 01, France

Email: pierre.perrot@chu-nantes.fr