Synfacts 2011(6): 0642-0642  
DOI: 10.1055/s-0030-1260439
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Copper-Catalyzed Asymmetric Conjugate Addition of Grignard Reagents

Contributor(s): Hisashi Yamamoto, Jiajing Tan
J. F. Teichert, B. L. Feringa*
University of Groningen, The Netherlands
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Publikationsverlauf

Publikationsdatum:
19. Mai 2011 (online)

Significance

The authors developed an efficient catalyst system for the asymmetric addition of Grignard reagents to inactivated courmarins. The desired products were obtained in good yields and enantioselectivities.