PDF herunterladen
Synfacts 2011(6): 0591-0591  
DOI: 10.1055/s-0030-1260370
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Syntheses of Guanacastepenes N and O

Contributor(s): Steven V. Ley, Sean Newton
C. M. Gampe, E. M. Carreira*
ETH Zürich, Switzerland
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
19. Mai 2011 (online)

   Lizenzen und Reprints

Significance

Guanacastepenes N and O belong to a family of diterpenes, isolated in 2001. They exhibit antibiotic activity and consist of an unpre­cedented tricyclic carbon skeleton and five stereogenic centers. Guanacastepenes N and O are epimeric at C13.