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Synfacts 2010(10): 1133-1133  
DOI: 10.1055/s-0030-1258637
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Triggered Microcapsule Depolymerization

Contributor(s): Timothy M. Swager, D. Barney Walker
A. P. Esser-Kahn, N. R. Sottos, S. R. White, J. S. Moore*
University of Illinois at Urbana-Champaign, USA
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Publication History

Publication Date:
22 September 2010 (online)

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Significance

A general route to programmable microcapsules that release their contents in response to specific stimuli is reported (inset). The vesicles are prepared by crosslinking self-immolative polymer 1 under conditions that promote the formation of discrete microcapsules. The authors prove that under appropriate ‘triggering’ conditions the walls of the isolated vesicles can be ruptured allowing trapped substrates to be released.