Paraneoplastische Syndrome beim Lungenkarzinom

Zusammenfassung

Paraneoplastische Syndrome treten bei ca. 10 % aller Patienten mit Lungenkrebs auf. Sie können die Erstmanifestation der Erankung oder ein erstes Zeichen für ein Rezidiv sein. Nach der klinischen Symptomatik können endokrine, hämatologische, neurologische, dermatologische, skelettale, renale, metabolische, kollagenose-vaskulitische und konstitutionelle Syndrome unterschieden werden. In der vorliegenden Übersichtsarbeit werden die Epidemiologie, Pathogenese, klinische Symptomatik und Therapieoptionen der wichtigsten paraneoplastischen Syndrome beim Lungenkarzinom dargestellt.

Abstract

Paraneoplastic syndromes occur in approximately 10 % of all patients with lung cancer. They can be the first manifestation of the disease or of a recurrence. Endocrine, haematological, neuromuscular, dermatological, renal, and metabolic syndromes as well as syndromes involving the connective tissue and constitutional syndromes can be distinguished based on their clinical symptoms. In this review, the epidemiology, pathogenesis, clinical signs and treatment options for the clinically important paraneoplastic syndromes in lung cancer are discussed.

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