Endoscopy 2011; 43(3): 236-239
DOI: 10.1055/s-0030-1255927
Case report/series

© Georg Thieme Verlag KG Stuttgart · New York

Risk factors for recurrence of artificial gastric ulcers after endoscopic submucosal dissection

Y.  Huang1 , N.  Kakushima1 , K.  Takizawa1 , M.  Tanaka1 , H.  Ikehara1 , Y.  Yamaguchi1 , H.  Matsubayashi1 , H.  Ono1 , T.  Oishi2 , T.  Nakajima2
  • 1Endoscopy Division, Shizuoka Cancer Center, Shizuoka, Japan
  • 2Pathology Division, Shizuoka Cancer Center, Shizuoka, Japan
Further Information

Publication History

submitted 29 July 2010

accepted after revision 21 September 2010

Publication Date:
24 November 2010 (online)

It has been reported previously that artificial gastric ulcers caused by endoscopic submucosal dissection (ESD) would heal within 8 weeks, irrespective of their size and location. The aim of this retrospective study was to describe long-term outcomes of gastric ESD ulcers. Check-up of ulcers was performed by periodic endoscopy. The rate of ESD ulcer recurrence and clinicopathological factors that may relate to recurrence were assessed. During the median observation period of 33 months, a benign ulcer recurrence occurred in 10 lesions in 10 patients (2.1 %). Univariate analysis showed that Helicobacter pylori infection and presence of pathological ulcer findings within the ESD specimen were significantly related to the risk of ESD ulcer recurrence. Although the frequency is low, there is a possibility of ESD ulcer recurrence in patients with H. pylori infection and in patients who undergo ESD for a lesion with ulceration.

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N. KakushimaMD, PhD 

Endoscopy Division
Shizuoka Cancer Center

1007 Shimonagakubo
Nagaizumi
Suntogun Shizuoka
411-8777
Japan

Fax: +81-55-9895783

Email: kakushin-tky@umin.ac.jp