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Thorac Cardiovasc Surg 2012; 60(01): 084-086
DOI: 10.1055/s-0030-1250638
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Heart Failure Resulting from Giant Left Atrial Synovial Sarcoma Metastasis

B. Winkler
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
,
M. Grapow
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
,
M. Seeberger
2   Department of Anaesthesia, University Hospital Basel, Basel, Switzerland
,
P. Matt
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
,
W. Aulitzky
3   Department of Haematology and Oncology, Robert Bosch Hospital, Stuttgart, Germany
,
F. Eckstein
1   Cardiac Surgery Basel, University Hospital Basel, Heart Surgery Centre Basel-Bern, Basel, Switzerland
› Author Affiliations
Further Information

Publication History

12 June 2010

15 October 2010

Publication Date:
21 March 2011 (online)

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Abstract

Synovial sarcoma metastasis affecting the heart and infiltrating the mitral valve is a very rare pathology. We report the case of a 44-year-old male treated with chemotherapy for atypical synovial sarcoma of the oral mucosa who presented to our clinic after cardiac decompensation with a presumptive diagnosis of myxoma of the left atrium. A large necrotic tumour positive for CK 22, EMA, CD 99 and BCL-2 but negative for translocation in COBRA-FISH analysis by break-apart probe could be excised and revealed a very rare subtype of synovial sarcoma metastasis arising from the endocard of the left atrium. The tumour was resected and the mitral valve reconstructed through ring annuloplasty.

Keywords

heart disease - heart valve surgery - cardiomyopathy
 

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