Zusammenfassung
Silikonöl wird als Tamponade in der Behandlung komplexer Netzhautablösungen mit proliferativer
Vitreoretinopathie verwendet. In letzter Zeit tauchten Fallserien auf, die einen zentralen
Visusverlust nach Amotiochirurgie mit Silikonöl beschreiben, trotz scheinbar guter
Visusprognose. In verschiedenen Berichten wurde die Migration von Silikonöl in Netzhaut
und Sehnerv nachgewiesen, in Tierexperimenten der großflächige Verlust myelinisierter
Sehnervenfasern beobachtet. Diese Fallberichte und mögliche Mechanismen des Visusverlusts
nach Silikonöl werden besprochen. Letztendlich sollte die zusätzliche Gefahr eines
zentralen Visusverlusts miteinbezogen werden, wenn die Entscheidung zwischen Silikonöl
und Gas als intravitreale Tamponade zu treffen ist.
Abstract
Silicone oil is used as intravitreal tamponading agent in surgery for rhegmatogenous
retinal detachment (RRD) cases complicated with proliferative vitreoretinopathy (PVR).
Recently, a number of case series have appeared where profound central visual loss
has been found in eyes after uncomplicated vitrectomy with silicone tamponade for
RRD in eyes with seemingly good visual potential. Several reports have demonstrated
the migration of silicone oil droplets into the retina and the optic nerve, others
the widespread loss of myelinated optic nerve fibres. These reports are reviewed,
and it is concluded that caution is warranted when silicone oil is used in eyes with
good visual potential. Finally the additional danger of central visual loss should
be taken into consideration when deciding to use silicone oil or gas as intravitreal
tamponade.
Schlüsselwörter
Netzhautablösung - Silikonöl - proliferative Vitreoretinopathie
Key words
retinal detachment - silicone oil - proliferative Vitreoretinopathy
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Dr. Anja Lux
Augenklinik, Universität Kopenhagen, SUND, Glostrup Hospital
Ndr. Ringvej 57
2600 Kopenhagen
Dänemark
Telefon: + 45/6 13 13 38 0
Fax: + 49/22 14 32 97 0
eMail: anja.lux@gmx.net