Intense Pulsed Light: What Works, What's New, What's Next

David H Ciocon; Andreas Boker; David J Goldberg

doi:10.1055/s-0029-1243077

Facial Plastic Surgery, Inhaltsverzeichnis

Facial Plast Surg 2009; 25(5): 290-300
DOI: 10.1055/s-0029-1243077

Intense Pulsed Light: What Works, What's New, What's Next

David H. Ciocon¹ , Andreas Boker² , David J. Goldberg¹ ^, ³ ^, ⁴

¹Skin Laser and Surgery Specialists of New York and New Jersey, New York, New York
²Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas
³Sanctuary Medical Aesthetic Center, Boca Raton, Florida
⁴Department of Dermatology, Mount Sinai School of Medicine, New York, New York

Abstract

ABSTRACT

Intense pulsed light technology has revolutionized the noninvasive treatment of a whole variety of cutaneous cosmetic problems. Today's machines are safer, more diverse, less painful, and readily available. Intense pulsed lights can be used to treat vascular and pigmented lesions and are used for facial rejuvenation and the removal of unwanted hair. Newer, less powerful home-device intense pulsed light sources will not replace those used in a physician's office but will augment the use of today's more powerful medical office systems.

KEYWORDS

Intense pulsed light - hair removal - photorejuvenation - photodynamic therapy

Volltext

Referenzen

REFERENCES

1 Goldberg D J. Laser- and light-based hair removal: an update. Expert Rev Med Devices. 2007; 4 253-260
2 Goldberg D J. Laser removal of pigmented and vascular lesions. J Cosmet Dermatol. 2006; 5 204-209
3 Anderson R R, Parrish J A. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science. 1983; 220 524-527
4 Raulin C, Greve B, Grema H. IPL technology: a review. Lasers Surg Med. 2003; 32 78-87
5 Ross E V. Laser versus intense pulsed light: competing technologies in dermatology. Lasers Surg Med. 2006; 38 261-272
6 Bjerring P, Christiansen K, Troilius A. Intense pulsed light source for the treatment of dye laser resistant port-wine stains. J Cosmet Laser Ther. 2003; 5 7-13
7 Ho W S, Ying S Y, Chan P C, Chan H H. Treatment of port wine stains with intense pulsed light: a prospective study. Dermatol Surg. 2004; 30 887-890 discussion 890-891
8 McGill D J, MacLaren W, Mackay I R. A direct comparison of pulsed dye, alexandrite, KTP and Nd:YAG lasers and IPL in patients with previously treated capillary malformations. Lasers Surg Med. 2008; 40 390-398
9 Ozdemir M, Engin B, Mevlitoğlu I. Treatment of facial port-wine stains with intense pulsed light: a prospective study. J Cosmet Dermatol. 2008; 7 127-131
10 Raulin C, Raulin S J, Hellwig S et al.. Treatment of benign venous malformations with an intense pulsed light source (PhotoDermTVL). Eur J Dermatol. 1997; 7 279-282
11 Raulin C, Hellwig S, Schönermark M P. Treatment of a nonresponding port-wine stain with a new pulsed light source (PhotoDerm VL). Lasers Surg Med. 1997; 21 203-208
12 Raulin C, Weiss R A, Schönermark M P. Treatment of essential telangiectasias with an intense pulsed light source (PhotoDerm VL). Dermatol Surg. 1997; 23 941-945 discussion 945-946
13 Clementoni M T, Gilardino P, Muti G F et al.. Intense pulsed light treatment of 1,000 consecutive patients with facial vascular marks. Aesthetic Plast Surg. 2006; 30 226-232
14 Raulin C, Schroeter C A, Weiss R A, Keiner M, Werner S. Treatment of port-wine stains with a noncoherent pulsed light source: a retrospective study. Arch Dermatol. 1999; 135 679-683
15 Reynolds N, Exley J, Hills S, Falder S, Duff C, Kenealy J. The role of the Lumina intense pulsed light system in the treatment of port wine stains—a case controlled study. Br J Plast Surg. 2005; 58 968-980
16 Faurschou A, Togsverd-Bo K, Zachariae C, Haedersdal M. Pulsed dye laser vs. intense pulsed light for port-wine stains: a randomized side-by-side trial with blinded response evaluation. Br J Dermatol. 2009; 160 359-364
17 Goldman M P, Weiss R A. Treatment of poikiloderma of Civatte on the neck with an intense pulsed light source. Plast Reconstr Surg. 2001; 107 1376-1381
18 Weiss R A, Goldman M P, Weiss M A. Treatment of poikiloderma of Civatte with an intense pulsed light source. Dermatol Surg. 2000; 26 823-827 discussion 828
19 Rusciani A, Motta A, Fino P, Menichini G. Treatment of poikiloderma of Civatte using intense pulsed light source: 7 years of experience. Dermatol Surg. 2008; 34 314-319 discussion 319
20 Papageorgiou P, Clayton W, Norwood S, Chopra S, Rustin M. Treatment of rosacea with intense pulsed light: significant improvement and long-lasting results. Br J Dermatol. 2008; 159 628-632
21 Neuhaus I M, Zane L T, Tope W D. Comparative efficacy of nonpurpuragenic pulsed dye laser and intense pulsed light for erythematotelangiectatic rosacea. Dermatol Surg. 2009; 35 920-928
22 Lucassen G W, Verkruysse W, Keijzer M, van Gemert M J. Light distributions in a port wine stain model containing multiple cylindrical and curved blood vessels. Lasers Surg Med. 1996; 18 345-357
23 Ortonne J P, Pandya A G, Lui H, Hexsel D. Treatment of solar lentigines. J Am Acad Dermatol. 2006; 54(5 Suppl 2) S262-S271
24 Yamashita T, Negishi K, Hariya T et al.. Intense pulsed light therapy for superficial pigmented lesions evaluated by reflectance-mode confocal microscopy and optical coherence tomography. J Invest Dermatol. 2006; 126 2281-2286
25 Kawada A, Asai M, Kameyama H et al.. Videomicroscopic and histopathological investigation of intense pulsed light therapy for solar lentigines. J Dermatol Sci. 2002; 29 91-96
26 Kawada A, Shiraishi H, Asai M et al.. Clinical improvement of solar lentigines and ephelides with an intense pulsed light source. Dermatol Surg. 2002; 28 504-508
27 Ross E V, Smirnov M, Pankratov M, Altshuler G. Intense pulsed light and laser treatment of facial telangiectasias and dyspigmentation: some theoretical and practical comparisons. Dermatol Surg. 2005; 31(9 Pt 2) 1188-1198
28 Moreno Arias G A, Ferrando J. Intense pulsed light for melanocytic lesions. Dermatol Surg. 2001; 27 397-400
29 Galeckas K J, Collins M, Ross E V, Uebelhoer N S. Split-face treatment of facial dyschromia: pulsed dye laser with a compression handpiece versus intense pulsed light. Dermatol Surg. 2008; 34 672-680
30 Wang C C, Hui C Y, Sue Y M, Wong W R, Hong H S. Intense pulsed light for the treatment of refractory melasma in Asian persons. Dermatol Surg. 2004; 30 1196-1200
31 Feng Y, Zhao J, Gold M H. Skin rejuvenation in Asian skin: the analysis of clinical effects and basic mechanisms of intense pulsed light. J Drugs Dermatol. 2008; 7 273-279
32 Li Y H, Chen J Z, Wei H C et al.. Efficacy and safety of intense pulsed light in treatment of melasma in Chinese patients. Dermatol Surg. 2008; 34 693-700 discussion 700-701
33 Anderson R R. Laser tissue interactions. In: Goldman MP, Fitzpatrick RE Cutaneous Laser Surgery. St. Louis, MO; Mosby Year Book 1994: 9-10
34 Sadick N S, Shea C R, Burchette Jr J L, Prieto V G. High-intensity flashlamp photoepilation: a clinical, histological, and mechanistic study in human skin. Arch Dermatol. 1999; 135 668-676
35 Gold M H, Bell M W, Foster T D, Street S. Long-term epilation using the EpiLight broad band, intense pulsed light hair removal system. Dermatol Surg. 1997; 23 909-913
36 Radmanesh M, Azar-Beig M, Abtahian A, Naderi A H. Burning, paradoxical hypertrichosis, leukotrichia and folliculitis are four major complications of intense pulsed light hair removal therapy. J Dermatolog Treat. 2008; 19 360-363
37 Amin S P, Goldberg D J. Clinical comparison of four hair removal lasers and light sources. J Cosmet Laser Ther. 2006; 8 65-68
38 Kalka K, Merk H, Mukhtar H. Photodynamic therapy in dermatology. J Am Acad Dermatol. 2000; 42 389-413 quiz 414-416
39 Hongcharu W, Taylor C R, Chang Y, Aghassi D, Suthamjariya K, Anderson R R. Topical ALA-photodynamic therapy for the treatment of acne vulgaris. J Invest Dermatol. 2000; 115 183-192
40 Gold M H, Bradshaw V L, Boring M M, Bridges T M, Biron J A. Split-face comparison of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light versus intense pulsed light alone for photodamage. Dermatol Surg. 2006; 32 795-801 discussion 801-803
41 Peng Q, Berg K, Moan J, Kongshaug M, Nesland J M. 5-Aminolevulinic acid-based photodynamic therapy: principles and experimental research. Photochem Photobiol. 1997; 65 235-251
42 Kloek J, Akkermans W, Beijersbergen van Henegouwen G M. Derivatives of 5-aminolevulinic acid for photodynamic therapy: enzymatic conversion into protoporphyrin. Photochem Photobiol. 1998; 67 150-154
43 Ruiz-Rodriguez R, Sanz-Sánchez T, Córdoba S. Photodynamic photorejuvenation. Dermatol Surg. 2002; 28 742-744 discussion 744
44 Dover J S, Bhatia A C, Stewart B, Arndt K A. Topical 5-aminolevulinic acid combined with intense pulsed light in the treatment of photoaging. Arch Dermatol. 2005; 141 1247-1252
45 Avram D K, Goldman M P. Effectiveness and safety of ALA-IPL in treating actinic keratoses and photodamage. J Drugs Dermatol. 2004; 3(1, Suppl) S36-S39
46 Gold M H, Bradshaw V L, Boring M M, Bridges T M, Biron J A. Split-face comparison of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light versus intense pulsed light alone for photodamage. Dermatol Surg. 2006; 32 795-801 discussion 801-803
47 Marmur E S, Phelps R, Goldberg D J. Ultrastructural changes seen after ALA-IPL photorejuvenation: a pilot study. J Cosmet Laser Ther. 2005; 7 21-24
48 Pollock B, Turner D, Stringer M R et al.. Topical aminolaevulinic acid-photodynamic therapy for the treatment of acne vulgaris: a study of clinical efficacy and mechanism of action. Br J Dermatol. 2004; 151 616-622
49 Divaris D XG, Kennedy J C, Pottier R H. Phototoxic damage to sebaceous glands and hair follicles of mice after systemic administration of 5-aminolevulinic acid correlates with localized protoporphyrin IX fluorescence. Am J Pathol. 1990; 136 891-897
50 Gold M H, Bradshaw V L, Boring M M, Bridges T M, Biron J A, Carter L N. The use of a novel intense pulsed light and heat source and ALA-PDT in the treatment of moderate to severe inflammatory acne vulgaris. J Drugs Dermatol. 2004; 3(6, Suppl) S15-S19
51 Santos M A, Belo V G, Santos G. Effectiveness of photodynamic therapy with topical 5-aminolevulinic acid and intense pulsed light versus intense pulsed light alone in the treatment of acne vulgaris: comparative study. Dermatol Surg. 2005; 31(8 Pt 1) 910-915
52 Yeung C K, Shek S Y, Bjerring P, Yu C S, Kono T, Chan H H. A comparative study of intense pulsed light alone and its combination with photodynamic therapy for the treatment of facial acne in Asian skin. Lasers Surg Med. 2007; 39 1-6
53 Downs A M, Bower C B, Oliver D A, Stone C A. Methyl aminolaevulinate-photodynamic therapy for actinic keratoses, squamous cell carcinoma in situ and superficial basal cell carcinoma employing a square wave intense pulsed light device for photoactivation. Br J Dermatol. 2009; 161 189-190
54 Goldberg D J, Cutler K B. Nonablative treatment of rhytids with intense pulsed light. Lasers Surg Med. 2000; 26 196-200
55 Bitter P H. Noninvasive rejuvenation of photodamaged skin using serial, full-face intense pulsed light treatments. Dermatol Surg. 2000; 26 835-842 discussion 843
56 Weiss R A, Weiss M A, Beasley K L. Rejuvenation of photoaged skin: 5 years results with intense pulsed light of the face, neck, and chest. Dermatol Surg. 2002; 28 1115-1119
57 Goldberg D J. New collagen formation after dermal remodeling with an intense pulsed light source. J Cutan Laser Ther. 2000; 2 59-61
58 Wong W R, Shyu W L, Tsai J W, Hsu K H, Pang J H. Intense pulsed light effects on the expression of extracellular matrix proteins and transforming growth factor beta-1 in skin dermal fibroblasts cultured within contracted collagen lattices. Dermatol Surg. 2009; 35 816-825
59 Hernández-Pérez E, Ibiett E V. Gross and microscopic findings in patients submitted to nonablative full-face resurfacing using intense pulsed light: a preliminary study. Dermatol Surg. 2002; 28 651-655
60 Zelickson B, Kist D. Pulsed dye laser and photoderm treatment stimulates production of type-1 collagen and collagenase transcripts in papillary dermis fibroblasts. Lasers Surg Med; Abstract Suppl. 2001; 13 132
61 Khoury J G, Saluja R, Goldman M P. The effect of botulinum toxin type A on full-face intense pulsed light treatment: a randomized, double-blind, split-face study. Dermatol Surg. 2008; 34 1062-1069
62 Carruthers J, Carruthers A. The effect of full-face broadband light treatments alone and in combination with bilateral crow's feet botulinum toxin type A chemodenervation. Dermatol Surg. 2004; 30 355-366 discussion 366
63 Hodson D S. Current and future trends in home laser devices. Semin Cutan Med Surg. 2008; 27 292-300
64 Alster T S, Tanzi E L. Effect of a novel low-energy pulsed-light device for home-use hair removal. Dermatol Surg. 2009; 35 483-489
65 Fodor L, Carmi N, Fodor A, Ramon Y, Ullmann Y. Intense pulsed light for skin rejuvenation, hair removal, and vascular lesions: a patient satisfaction study and review of the literature. Ann Plast Surg. 2009; 62 345-349

David J GoldbergM.D.

Skin Laser and Surgery Specialists of New York and New Jersey

115 E. 57th Street, Suite 710, New York, NY 10022