Diagnosis and Hemodynamic Assessment of Pulmonary Arterial Hypertension

Rajan Saggar; Rajeev Saggar; Jamil Aboulhosn; John A Belperio; David A Zisman; Joseph P Lynch

doi:10.1055/s-0029-1233309

Seminars in Respiratory and Critical Care Medicine, Table of Contents

Semin Respir Crit Care Med 2009; 30(4): 399-410
DOI: 10.1055/s-0029-1233309

Diagnosis and Hemodynamic Assessment of Pulmonary Arterial Hypertension

Rajan Saggar¹ , Rajeev Saggar¹ , Jamil Aboulhosn¹ , John A. Belperio¹ , David A. Zisman¹ , Joseph P. Lynch¹

¹Division of Pulmonary, Critical Care Medicine, and Hospitalists, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California

Abstract

ABSTRACT

Pulmonary hypertension (PH) can occur as either a primary or a secondary process, and in general, its presence increases overall morbidity and mortality. Importantly, the majority of prior studies have been in the setting of idiopathic pulmonary arterial hypertension (IPAH); thus the following discussion focuses on IPAH. Because the majority of available diagnostic strategies lack sensitivity and specificity, the physician must maintain a high index of suspicion in considering PAH. This article provides an overview of the available diagnostic studies for PAH with a particular focus on hemodynamic assessment. Novel approaches to the often delayed diagnosis of PAH are being studied and are also discussed here.

KEYWORDS

Pulmonary hypertension - hemodynamic - echocardiogram - diagnosis - right heart catheterization

Full Text

References

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Rajan SaggarM.D.

Division of Pulmonary, Critical Care Medicine, and Hospitalists, David Geffen School of Medicine at UCLA

18033 Le Conte Ave., 37-131 CHS, Los Angeles, CA 90095-1690

Email: rsaggar@mednet.ucla.edu