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Synfacts 2010(2): 0212-0212  
DOI: 10.1055/s-0029-1219059
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Ni-Catalyzed Amination of Diorganozinc Compounds with N-Chloroamines

Contributor(s): Paul Knochel, Andrei Gavryushin
T. J. Barker, E. R. Jarvo*
University of California, Irvine, USA
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Publikationsdatum:
21. Januar 2010 (online)

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Significance

A simple catalytic method for amination of arylzinc compounds by N-chloroamines is reported. Acyclic and cyclic chloroamines are effective amination agents in this reaction. Various arylzinc derivatives can be used. A convenient procedure for the one-pot chlorination with N-chlorosuccinimide (NCS) and amination has also been developed.