The 1,2,4-Triazole Anion as an Acyl Transfer Catalyst

Significance

Yang and Birman report that the 1,2,4-triazole anion is an acyl transfer catalyst. The acetylation proved to be effective for amines, alcohols and oxazolidinones. This catalyst is also suitable for transesterification as well as for amino­lysis, where unactivated esters can be transformed into the corresponding products. Mechanistic alternatives have been investigated.