Zusammenfassung
Die Implantation elektronischer Netzhautstimulatoren wird künftig eine Möglichkeit
sein, bei Patienten, die aufgrund einer degenerativen Netzhauterkrankung erblindet
sind, die Sehfähigkeit partiell wieder herzustellen. Die Idee solcher Sehprothesen
ist nicht neu, sie scheint aber aufgrund des allgemeinen technischen Fortschritts
nun realisierbar zu werden. Sehprothesen können an jeder Stelle des visuellen Systems
integriert werden. So gibt es subretinale und epiretinale Netzhautstimulatoren sowie
Stimulatoren, die direkt mit dem Sehnerv verbunden werden. Auch Versuche einer direkten
Stimulation der Sehrinde sind unternommen worden. Mehrere große Konsortien verfolgen
momentan die epiretinale Stimulation. Grundsätzlich bleibt das große Problem der Signalmodulation
zu lösen, sodass über den Stimulator dem Gehirn eine interpretierbare Sehinformation
zur Verfügung gestellt wird. Der Artikel fasst unter Berücksichtigung aktueller Beiträge
die gegenwärtigen Konzepte zusammen.
Abstract
The implantation of electronic retina stimulators appears to be a future possibility
to restore vision, at least partially in patients with retinal degeneration. The idea
of such visual protheses is not new but due to the general technical progress it has
become more likely that a functioning implant will be on the market soon. Visual prosthesis
may be integrated in the visual system in various places. Thus there are subretinal
and epiretinal implants, as well as implants that are connected directly to the optic
nerve or the visual cortex. The epiretinal approach is the most promising at the moment,
but the problem of appropriate modulation of the image information is unsolved so
far. This will be necessary to provide a interpretable visual information to the brain.
The present article summarises the concepts and includes some latest information from
recent conferences.
Schlüsselwörter
Retina - Informationstechnologie - Elektrophysiologie
Key words
retina - information technology - electrophysiology
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PD Dr. Oliver Zeitz
Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Hamburg-Eppendorf
Martinistr. 52
20246 Hamburg
Telefon: ++ 49/40/4 28 03 33 14
Fax: ++ 49/40/4 28 03 88 84
eMail: zeitz@uke.uni-hamburg.de