Zusammenfassung
Präzise Fragestellungen und weitere wesentliche Voraussetzungen für eine sinnvolle
Auswertung werden erörtert. Für jede Fragestellung werden, falls vorhanden, geeignete
Auswertungsmodelle angegeben.
Summary
Any reasonable evaluation presupposes a precise question. Furthermore it is necessary
to eliminate all factors of disturbance, which are able either to simulate or to mask
a result of evaluation. The most important of these factors is the psychiatrist himself.
Therefore, experimental designs have to taken in account the factor psychiatrist.
Criteria of the effects of any drug must be relevant with regard to comparison of
two ore more drug effects. The reproduciability of criteria is very desirable, but
a wish-fulfilment under the most circumstances. Because criteria should be independent
and mutually exclusive, all scales like the Hamiltons one are not suitable for evaluation. Finally one should use as few criteria as possible.
Models of evaluation are described far the most frequent questions in connection with
clinical trials in psychopharmacology.