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DOI: 10.1055/a-2606-7785
Clinical effectiveness of esophageal stricture dilation using an improved endoscopic attachment cap in adults with eosinophilic esophagitis
Supported by: Swiss National Science Foundation (to Alain Schoepfer) 32003B_204751/1
Supported by: SWISS EOE FOUNDATION to Alain Schoepfer

Abstract
Background
The improved endoscopic attachment cap has the following new features: 1) more rounded tip; 2) stepwise dilation in two 1-mm increments; 3) softer plastic, ensuring better contact with the endoscope tip; and 4) improved adhesive tape. We evaluated the feasibility and effectiveness of one-time esophageal stricture dilation using the new device in adults with eosinophilic esophagitis (EoE).
Methods
Patients prospectively included in the Swiss EoE cohort with esophageal strictures (diameter ≤16 mm) and stricture-related symptoms underwent dilation with the new device. Symptoms were assessed using the Eosinophilic Esophagitis Activity Index patient-reported outcomes instrument before and 2 weeks after a single dilation.
Results
60 patients (median age 42 years; 75% male) were evaluated. Bougienage was successful in all patients. Median esophageal diameter increased from 12 mm (interquartile range [IQR] 11–14) to 16 mm (IQR 14–16; P < 0.001). Median symptom severity dropped from 36 points (IQR 22–62) to 0 (IQR 0–12; P < 0.001). No device became detached and no severe adverse events were reported. Post-dilation pain was recorded in 31.7% (19/60).
Conclusions
Esophageal stricture dilation in adults with EoE using the improved endoscopic attachment cap was feasible, clinically effective, and environmentally friendly.
Publication History
Received: 03 December 2024
Accepted after revision: 02 April 2025
Article published online:
04 June 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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References
- 1 Lucendo AJ, Molina-Infante J, Arias A. et al. Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations of diagnosis and management in children and adults. United European Gastroenterol J 2017; 5: 335-358
- 2 Attwood SE, Smyrk TC, Demeester TR. et al. Esophageal eosinophilia with dysphagia: a distinct clinicopathologic syndrome. Dig Dis Sci 1993; 38: 109-116
- 3 Dellon ES, Hirano I. Epidemiology and natural history of eosinophilic esophagitis. Gastroenterology 2018; 154: 319-332
- 4 Schoepfer AM, Safroneeva E, Bussmann C. et al. Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation, in a time-dependent manner. Gastroenterology 2013; 145: 1230-1236
- 5 Arias-González L, Rey-Iborra E, Ruiz-Ponce M. et al. Esophageal perforation in eosinophilic esophagitis: a systematic review on clinical presentation, management and outcomes. Dig Liver Dis 2020; 52: 245-252
- 6 Rank MA, Sharaf RN, Furuta GT. et al. Technical review on the management of eosinophilic esophagitis: a report from the AGA Institute and the Joint Task Force on Allergy-Immunology Practice Parameters. Gastroenterology 2020; 158: 1789-1810
- 7 Aceves SS, Alexander JA, Baron TH. et al. Endoscopic approach to eosinophilic esophagitis: American Society for Gastrointestinal Endoscopy Consensus Conference. Gastrointest Endosc 2022; 96: 576-592
- 8 Dougherty M, Runge TM, Eluri S. et al. Esophageal dilation with either bougie or balloon technique as a treatment for eosinophilic esophagitis: a systematic review and meta-analysis. Gastrointest Endosc 2017; 86: 581-559
- 9 Schoepfer AM, Henchoz S, Biedermann L. et al. Technical feasibility, clinical effectiveness, and safety of esophageal stricture dilation using a novel endoscopic attachment cap in adults with eosinophilic esophagitis. Gastrointest Endosc 2021; 94: 912-919.e2
- 10 Walter B, Schmidbaur S, Rahman I. et al. The BougieCap – a new method for endoscopic treatment of complex benign esophageal stenosis: results from a multicenter study. Endoscopy 2019; 51: 866-870
- 11 Ovesco Endoscopy AG. BougieCap. Accessed March 08, 2024 at: https://ovesco.com/scopecaps/bougiecap/
- 12 Yzet C, Figueiredo M, Michoud C. et al. Ecological impact of endoscopic dilatation using the bougie cap device: a low-tech innovation to reduce waste by 99%. Endoscopy 2022; 54 (Suppl. 02) E824-E825
- 13 Wakim El-Khoury J, Safroneeva E, Saner C. et al. Cohort profile update: the Swiss Eosinophilic Esophagitis Cohort Study (SEECS). Inflamm Intest Dis 2024; 9: 165-173
- 14 REDCap. Accessed June 12, 2024 at: https://projectredcap.org/about/
- 15 Schoepfer AM, Straumann A, Panczak R. et al. Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis. Gastroenterology 2014; 147: 1255-1266
- 16 Lucendo AJ, Miehlke S, Schlag C. et al. Efficacy of budesonide orodispersible tablets as induction therapy for eosinophilic esophagitis in a randomized placebo-controlled trial. Gastroenterology 2019; 157: 74-86
- 17 Hirano I, Moy N, Heckman MG. et al. Endoscopic assessment of the oesophageal features of eosinophilic esophagitis: validation of a novel classification and grading system. Gut 2013; 62: 489-495
- 18 Sami SS, Haboubi HN, Ang Y. et al. UK guidelines on oesophageal dilatation in clinical practice. Gut 2018; 67: 1000-1023
- 19 Baddeley R, Aabakken L, Veitch A. et al. Green endoscopy: counting the carbon cost of our practice. Gastroenterology 2022; 162: 1556-1560