Open Access
CC BY 4.0 · Thromb Haemost
DOI: 10.1055/a-2595-1811
Review Article

Consensus on the Management of the Clinical Challenges of Venous Thromboembolism in Special Situations

Cristina Marzo
1   Hematology and Hemotherapy Department, Hospital Universitari Arnau de Vilanova, Lleida, Catalunya, Spain
,
Teresa Solanich
2   Vascular Surgery Department, Hospital Universitari Parc Taulí, Sabadell, Spain
,
Dolors Tassies
3   Hemotherapy and Hemostasis Department, Hospital Clinic Barcelona, Barcelona, Catalunya, Spain
,
Elena Pina
4   Thrombosis and Haemostasis Department, Hospital Universitari Bellvitge, Hospitalet de Llobregat, Barcelona, Spain
,
Maite Antonio Rebollo
5   Oncogeriatrics Unit, Institut Català d'Oncologia, Barcelona, Spain
,
Enrique Gallardo
6   Oncology, Parc Taulí Hospital Universitari, Sabadell, Barcelona, Spain
7   Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Barcelona, Spain
,
Sonia Serradell
8   Medical Oncology Department, Vall d'Hebron University Hospital, Barcelona, Spain
,
Marta Merino
9   Medical Affairs Thrombosis, LEO Pharma Spain, Barcelona, Spain
,
Marina Carrasco
10   Unitat d'Hemostasia i Trombosi, Servei d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
,
Albert Tugues
11   Hematology and Hemotherapy Department, Hospital Universitario Arnau de Vilanova de Lleida, Barcelona, Spain
› Author Affiliations


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Abstract

Venous thromboembolism (VTE) can present different challenging situations for which high-quality evidence to guide optimal preventive and therapeutic management is lacking and for which clinical practice guidelines have not established solid recommendations. The aim of this article is to achieve consensus on a proposal of action for the clinical management of complex, clinically relevant situations with a low level of evidence which generate great uncertainty—the duration of VTE treatment and the role of thrombus recanalization, the prevention of VTE within the context of pregnancy, management of anticoagulant treatment in patients with VTE and special characteristics, such as renal insufficiency and obesity, the therapeutic management of pluripathological and polymedicated older patients with VTE, and finally, primary ambulatory thromboembolic prevention in cancer patients. This consensus article arose from a collaboration of experts in VTE from different medical specialties.



Publication History

Received: 03 July 2024

Accepted: 16 December 2024

Article published online:
13 May 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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