Download PDF
CC BY 4.0 · Klin Monbl Augenheilkd
DOI: 10.1055/a-2550-0839
Der interessante Fall

Spontaneous Closure of Full-Thickness Macular Hole in a Patient with Retinal Arteriovenous Malformation: Sixteen-Year Follow-up

Spontaner Verschluss eines durchgreifenden Makulaforamens bei einem Patienten mit retinaler arteriovenöser Malformation: 16-jährige Nachbeobachtung
Zeynep Serikoglu Akbas 
1   Department of Ophthalmology, Istanbul University Cerrahpasa, Faculty of Medicine, Fatih, Turkey
,
Faik Gelisken
2   Department of Ophthalmology, University Hospital Tübingen, Germany
,
Benedikt Rössler
2   Department of Ophthalmology, University Hospital Tübingen, Germany
› Author Affiliations
› Further Information
Also available at
  Permissions and Reprints

Introduction

Retinal arteriovenous malformation (RAM), also known as retinal racemose haemangioma (RRH), is a congenital, non-hereditary, and sporadic vascular anomaly characterised by the appearance of dilated and tortuous abnormal retinal vessels. When accompanied by vascular malformations in the midbrain, mandible, or other parts of the body, it is referred to as Wyburn-Masonʼs disease [1], [2], [3].

Although RAM is typically asymptomatic and stable, complications such as central retinal vein occlusion, retinal ischaemia, and vitreous haemorrhage have been documented [4].

This report details a case of RAM complicated by central retinal vein occlusion and secondary full-thickness macular hole (FTMH) with spontaneous closure during follow-up of sixteen years.



Publication History

Accepted Manuscript online:
03 March 2025

Article published online:
16 June 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

  • References

  • 1 Akter N, Abousamra A. Education: Retinal racemose hemangioma arteriovenous malformation investigations, clinical course and management. Acta Ophthalmol 2023; 101: e346
    Search in Google Scholar
  • 2 Tuchen S, Vorwerk C, Behrens-Baumann W. Arteriovenöse Malformation Wyburn-Mason. Klin Monbl Augenheilkd 2010; 227 - D31
    Search in Google Scholar
  • 3 Schmidt D, Pache M, Schumacher M. The congenital unilateral retinocephalic vascular malformation syndrome (bonnet-dechaume-blanc syndrome or wyburn-mason syndrome): review of the literature. Surv Ophthalmol 2008; 53 (03) 227-249
    Search in Google Scholar
  • 4 Qin XJ, Huang C, Lai K. Retinal vein occlusion in retinal racemose hemangioma: a case report and literature review of ocular complications in this rare retinal vascular disorder. BMC Ophthalmol 2014; 14
    Search in Google Scholar
  • 5 Muñoz FJ, Rebolleda G, Cores FJ. et al. Congenital retinal arteriovenous communication associated with a full‐thickness macular hole. Acta Ophthalmol 1991; 69: 117-120
    Search in Google Scholar
  • 6 Glacet-Bernard A, Voigt M, Coscas G. et al. Full-thickness macular hole following intravitreal injection of triamcinolone acetonide in central retinal vein occlusion. Retin Cases Brief Rep 2007; 1: 62-64
    Search in Google Scholar
  • 7 Goel N. Full-thickness macular hole formation and spontaneous closure during intravitreal ranibizumab therapy for central retinal vein occlusion. Retin Cases Brief Rep 2022; 16: 678-680
    Search in Google Scholar
  • 8 Uwaydat SH, Mansour A, Ascaso FJ. et al. Clinical characteristics of full thickness macular holes that closed without surgery. Br J Ophthalmol 2022; 106: 1463
    Search in Google Scholar