Abstract
Objective
The effects of covid vaccination on the fetus and placenta make pregnant women a special
group in the vaccination series. Coronavirus vaccines are associated with endocrine
complications such as thyroid disease.
Study Design
The study included pregnant women who received the corona virus disease 2019 (COVID-19)
vaccine. Pregnant women were divided into three study groups; group A (who have not
received the COVID-19 vaccine), group B (who received the Sinopharm vaccine during
pregnancy), and group C (who received the Sinopharm vaccine before pregnancy). Blood
samples were taken to measure thyroid stimulating hormone (TSH) levels in infants
3 to 5 days old. Neonatal TSH values below 5 mU/L are considered normal.
Results
Sinopharm/BBIBP-CorV during and/or before pregnancy was associated with a slight increase
in mean TSH in newborns.
Conclusion
Vaccination with Sinopharm/BBIBP-CorV during or before pregnancy may slightly increase
neonatal TSH levels, but this is not clinically significant.
Key Points
-
COVID-19 vaccines linked to endocrine disruption.
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Sinopharm CorV during pregnancy triggers TSH in infants.
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Sinopharm vaccination in pregnancy increases neonatal TSH levels.
Keywords
COVID-19 - thyroid-stimulating hormone - Sinopharm/BBIBP-CorV
