Komplementärmedizinische Behandlungsmöglichkeiten bei chronisch-entzündlichen Darmerkrankungen

Christine Huber

doi:10.1055/a-2518-9146

Zeitschrift für Komplementärmedizin, Table of Contents

Zeitschrift für Komplementärmedizin 2025; 17(02): 14-19
DOI: 10.1055/a-2518-9146

Praxis

Chronisch-entzündliche Darmerkrankungen

Komplementärmedizinische Behandlungsmöglichkeiten bei chronisch-entzündlichen Darmerkrankungen

Christine Huber

Abstract

Summary

Chronisch-entzündliche Darmerkrankungen bleiben trotz des Fortschritts der konventionellen Behandlungsmöglichkeiten weiterhin eine Herausforderung für Behandler und Patient*innen. Wachsende wissenschaftliche Erkenntnisse über prädisponierende Faktoren und Einflussmöglichkeiten eröffnen neue Behandlungsansätze: Die Komplementärmedizin bietet dabei zunehmend evidenzgestützte Therapieoptionen, wie Akupunktur oder phytotherapeutische Behandlungsansätze.

Keywords

chronisch-entzündliche Darmerkrankungen - Komplementärmedizin - Mikrobiomdiversität - Phytotherapie - Colitis ulcerosa - Morbus Crohn

Full Text

References

Literatur
1 Albrecht U, Müller V, Schneider B. et al Efficacy and safety of a herbal medicinal product containing myrrh, chamomile and coffee charcoal for the treatment of gastrointestinal disorders: A non-interventional study.. BMJ Open Gastroenterol 2015; 1 (01) e000015
2 Ananthakrishnan AN, Long MD, Martin CF. et al Sleep disturbance and risk of active disease in patients with Crohn's disease and ulcerative colitis.. Clin Gastroenterol Hepatol 2013; 11 (08) 965-971
3 Bae JH, Kang SY, You SE. et al The effects of acupuncture on Crohn's disease: A systematic review and meta-analysis.. J Pharmacopuncture 2023; 26 (03) 211-226
4 Bao CH, Zhao JM, Liu HR. et al Randomized controlled trial: Moxibustion and acupuncture for the treatment of Crohn's disease.. World J Gastroenterol 2014; 20 (31) 11000-11011
5 Barberio B, Zamani M, Black CJ. et al Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: A systematic review and meta-analysis.. Lancet Gastroenterol Hepatol 2021; 6 (05) 359-370
6 Biedermann L, Doulberis M, Schreiner P. et al A multi-center randomized, double-blind, placebo controlled, parallel group, phase IIa study to evaluate the efficacy, safety and tolerability of an anthocyanin rich extract (ACRE) in patients with ulcerative colitis.. medRxiv 2024.
7 Biedermann L, Mwinyi J, Scharl M. et al Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis – an open pilot study.. J Crohns Colitis 2013; 7 (04) 271-279
8 Bryant RV, Trott MJ, Bartholomeusz FD. et al Systematic review: Body composition in adults with inflammatory bowel disease.. Aliment Pharmacol Ther 2013; 38 (03) 213-225
9 Cappellini MD, Comin-Colet J, de Francisco A. et al Iron deficiency across chronic inflammatory conditions: International expert opinion on definition, diagnosis, and management.. Am J Hematol 2017; 92 (10) 1068-1078
10 Chassaing B, Koren O, Goodrich JK. et al Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.. Nature 2015; 519 7541 92-96
11 Cox SR, Prince AC, Myers CE. et al Fermentable carbohydrates [FODMAPs] exacerbate functional gastrointestinal symptoms in patients with inflammatory bowel disease: A randomised, double-blind, placebo-controlled, cross-over, re-challenge trial.. J Crohns Colitis 2017; 11 (12) 1420-1429
12 Cramer H, Schäfer M, Schöls M. et al Randomised clinical trial: Yoga vs written self-care advice for ulcerative colitis.. Aliment Pharmacol Ther 2017; 45 (11) 1379-1389
13 Fernández-Bañares F, Hinojosa J, Sánchez-Lombraña JL. et al Randomized clinical trial of Plantago ovata seeds (dietary fiber) as compared with mesalamine in maintaining remission in ulcerative colitis. Spanish Group for the Study of Crohn's Disease and Ulcerative Colitis (GETECCU).. Am J Gastroenterol 1999; 94 (02) 427-433
14 Forbes A, Escher J, Hébuterne X. et al ESPEN guideline: Clinical nutrition in inflammatory bowel disease.. Clin Nutr 2017; 36 (02) 321-347
15 Gerhardt H, Seifert F, Buvari P. et al Therapie des aktiven Morbus Crohn mit dem Boswellia-serrata-Extrakt H 15.. Z Gastroenterol 2001; 39 (01) 11-17
16 Guan Q.. A Comprehensive review and update on the pathogenesis of inflammatory bowel disease.. J Immunol Res 2019; 7247238
17 Gupta I, Parihar A, Malhotra P. et al Effects of gum resin of Boswellia serrata in patients with chronic colitis.. Planta Med 2001; 67 (05) 391-395
18 Hanai H, Iida T, Takeuchi K. et al Curcumin maintenance therapy for ulcerative colitis: Randomized, multicenter, double-blind, placebo-controlled trial.. Clin Gastroenterol Hepatol 2006; 4 (12) 1502-1506
19 Hilsden RJ, Verhoef MJ, Rasmussen H. et al Use of complementary and alternative medicine by patients with inflammatory bowel disease.. Inflamm Bowel Dis 2011; 17 (02) 655-662
20 Huber R, Ditfurth AV, Amann F. et al Tormentil for active ulcerative colitis: An open-label, dose-escalating study.. J Clin Gastroenterol 2007; 41 (09) 834-838
21 Jairath V, Feagan BG.. Global burden of inflammatory bowel disease.. Lancet Gastroenterol Hepatol 2020; 5 (01) 2-3
22 Kairey L, Schröder D, Lauche R. et al Nutzung von komplementären und naturheilkundlichen Verfahren bei chronisch entzündlichen Darmerkrankungen in Deutschland.. Z Phytother 2019; 14 (01) P14
23 Keefer L, Taft TH, Kiebles JL. et al Gut-directed hypnotherapy significantly augments clinical remission in quiescent ulcerative colitis.. Aliment Pharmacol Ther 2013; 38 (07) 761-771
24 Khaki-Khatibi F, Qujeq D, Kashifard M. et al Calprotectin in inflammatory bowel disease.. Clin Chim Acta 2020; 510: 556-565
25 Khalili H, Higuchi LM, Ananthakrishnan AN. et al Oral contraceptives, reproductive factors and risk of inflammatory bowel disease.. Gut 2013; 62 (08) 1153-1159
26 Langhorst J, Wulfert H, Lauche R. et al Systematic review of complementary and alternative medicine treatments in inflammatory bowel diseases.. J Crohns Colitis 2015; 9 (01) 86-106
27 Lee A, Moulton D, Mckernan L. et al Clinical hypnosis in pediatric Crohn's disease: A randomized controlled pilot study.. J Pediatr Gastroenterol Nutr 2021; 72 (03) e63-e70
28 Lo CH, Lochhead P, Khalili H. et al Dietary inflammatory potential and risk of Crohn's disease and ulcerative colitis.. Gastroenterology 2020; 159 (03) 873-883
29 Long MD, Kappelman MD, Martin CF. et al Role of nonsteroidal anti-inflammatory drugs in exacerbations of inflammatory bowel disease.. J Clin Gastroenterol 2016; 50 (02) 152-156
30 Losurdo G, Iannone A, Contaldo A. et al Escherichia coli Nissle 1917 in ulcerative colitis treatment: Systematic review and meta-analysis.. J Gastrointestin Liver Dis 2015; 24 (04) 499-505
31 Ma Y, Yang D, Huang J. et al Probiotics for inflammatory bowel disease: Is there sufficient evidence?. Open Life Sci 2024; 19 (01) 20220821
32 Marinelli C, Savarino EV, Marsilio I. et al Sleep disturbance in inflammatory bowel disease: Prevalence and risk factors – A cross-sectional study.. Sci Rep 2020; 10 (01) 507
33 Mentella MC, Scaldaferri F, Pizzoferrato M. et al Nutrition, IBD and gut microbiota: A review.. Nutrients 2020; 12 (04) 944
34 Molodecky NA, Soon IS, Rabi DM. et al Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review.. Gastroenterology 2012; 142 (01) 46-54e30
35 Mpakogiannis K, Fousekis FS, Katsanos AH. et al Can hypnotherapy be considered a valuable component in the management of inflammatory bowel disease? Insights from a comprehensive review.. Int J Clin Exp Hypn 2024; 72 (03) 274-288
36 Omer B, Krebs S, Omer H. et al Steroid-sparing effect of wormwood (Artemisia absinthium) in Crohn's disease: A double-blind placebo-controlled study.. Phytomedicine 2007; 14 2-3 87-95
37 Ott C, Takses A, Obermeier F. et al Smoking increases the risk of extraintestinal manifestations in Crohn's disease.. World J Gastroenterol 2014; 20 (34) 12269-12276
38 Peters SL, Muir JG, Gibson PR.. Review article: Gut-directed hypnotherapy in the management of irritable bowel syndrome and inflammatory bowel disease.. Aliment Pharmacol Ther 2015; 41 (11) 1104-1115
39 Rastegarpanah M, Malekzadeh R, Vahedi H. et al A randomized, double blinded, placebo-controlled clinical trial of silymarin in ulcerative colitis.. Chin J Integr Med 2015; 21 (12) 902-906
40 Sabir G, Abdelhady HA, Oumar Abakar A. et al The potential benefits of exercise in managing inflammatory bowel disease: A systematic review.. Cureus 2024; 16 (09) e68948
41 Sartor RB, Wu GD.. Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches.. Gastroenterology 2017; 152 (02) 327-339.e4
42 Sharma P, Poojary G, Dwivedi SN. et al Effect of yoga-based intervention in patients with inflammatory bowel disease.. Int J Yoga Therap 2015; 25 (01) 101-112
43 Shaw SY, Blanchard JF, Bernstein CN.. Association between the use of antibiotics and new diagnoses of Crohn's disease and ulcerative colitis.. Am J Gastroenterol 2011; 106 (12) 2133-2142
44 Talebi S, Zeraattalab-Motlagh S, Rahimlou M. et al The association between total protein, animal protein, and animal protein sources with risk of inflammatory bowel diseases: A systematic review and meta-analysis of cohort studies.. Adv Nutr 2023; 14 (04) 752-761
45 Wang X, Zhao NQ, Sun YX. et al Acupuncture for ulcerative colitis: A systematic review and meta-analysis of randomized clinical trials.. BMC Complement Med Ther 2020; 20 (01) 309
46 Weiß M.. „Cannabis-Eigentherapie“ bei chronisch-entzündlichen Darmerkrankungen weit verbreitet. Medical Tribune. Im Internet:. https://www.medical-tribune.de/medizin-und-forschung/artikel/cannabis-eigentherapie-bei-chronisch-entzndlichen-darmerkrankungen-weit-verbreitet?utm_source=chatgpt.com Stand: 11.03.2025
47 World Health Organization (WHO). WHO traditional medicine strategy: 2014–2023. Geneva: World Health Organization; 2013. Im Internet:. https://www.who.int/publications/i/item/9789241506096 Stand: 06.03.2025
48 Xu L, Lochhead P, Ko Y. et al Systematic review with meta-analysis: Breastfeeding and the risk of Crohn's disease and ulcerative colitis.. Aliment Pharmacol Ther 2017; 46 (09) 780-789
49 Zezos P, Nguyen GC.. Use of complementary and alternative medicine in inflammatory bowel disease around the world.. Gastroenterol Clin North Am 2017; 46 (04) 679-688
50 Zhao M, Feng R, Ben-Horin S. et al Systematic review with meta-analysis: Environmental and dietary differences of inflammatory bowel disease in Eastern and Western populations.. Aliment Pharmacol Ther 2022; 55 (03) 266-276
51 Mardini HE, Grigorian AY.. Probiotic mix VSL#3 is effective adjunctive therapy for mild to moderately active ulcerative colitis: A meta-analysis.. Inflamm Bowel Dis 2014; 20 (09) 1562-1567