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Tierarztl Prax Ausg K Kleintiere Heimtiere 2025; 53(01): 34-46
DOI: 10.1055/a-2516-6222
DOI: 10.1055/a-2516-6222
Übersichtsartikel
Tiermedizinische Versorgung von Minischweinen – eine Herausforderung für die Kleintierpraxis
Veterinary care for minipigs – a challenge for small animal practice
Zusammenfassung
Miniaturschweine, kurz Minischweine, wurden ursprünglich zu Versuchszwecken gezüchtet. Seit den 1990er Jahren werden sie als Heimtiere in privaten Haushalten gehalten. Haltungen in Wohnungen, Stallgebäuden mit Ausläufen und im Freiland kommen gleichermaßen vor. Fehler in der Fütterung und unzureichendes Wissen der Tierhalter über ihre Tiere führen häufig zu haltungsbedingten Erkrankungen. Im Falle von Krankheiten oder für notwendige Pflegemaßnahmen werden meist Kleintierpraxen aufgesucht. In der vorliegenden Übersichtsarbeit werden die Themen Zuchtlinien, Haltung, Fütterung, rechtliche Grundlagen, klinische Untersuchung, die wichtigsten Krankheiten sowie deren Behandlung vorgestellt.
Abstract
Miniature pet pigs, called Minipigs, were originally bred for experimental purposes. Since the 1990s, they have been kept as pets in private households. They are kept indoor, in stables with runs and outdoors. Mistakes in feeding and insufficient knowledge of pet owners about their animals lead to husbandry-related diseases. Veterinary practices for small animals are often visited in the case of disease or necessary care measures. In this review, the topics of breeding lines, husbandry, feeding, legal principles, clinical examination, the most important diseases and their treatment are presented.
Schlüsselwörter
Hobbyschweine - Rechtliche Grundlagen - Privathaltung - Klinische Untersuchung - BehandlungPublikationsverlauf
Eingereicht: 23. April 2024
Angenommen: 08. Januar 2025
Artikel online veröffentlicht:
18. Februar 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
- 1 Simianer H, Köhn F. Genetic management of the Göttingen minipig population. J Pharmacol Toxicol Methods 2010; 62: 221-226
- 2 Taylor M. Suidae – The pig family. In: Pot-bellied pigs as your new family pet. Neptune City, New Jersey: TFH Publications; 1993: 43-46 ISBN: 9780866220811
- 3 Erhard M. Haltung exotischer Tiere und Wildtiere in Privathand: Situationsanalyse, Bewertung und Handlungsbedarf insbesondere unter Tierschutzaspekten – 2. Zwischenbericht exotische Säugetiere und Wildtiere. LMU München 2010. URL: https://service.ble.de/ptdb/index2.php?detail_id=56943&ssk=9ddea1dad7&site_key=145&stichw=2815HS001&zeilenzahl_zaehler=1#newContent
- 4 Braun WF, Casteel SW. Potbellied pigs. Miniature porcine pets. Vet Clin North Am Small Anim Pract 1993; 23: 1149-1177
- 5 Bollen P, Ritskes-Hoitinga M. Chapter 12 The welfare of pigs and minipigs. In: Kaliste E, ed. The welfare of laboratory animals. 1st ed. Dordrecht: Springer; 2007: 275-289
- 6 Reimer C, Rubin C-J, Sharifi AR. et al. Analysis of porcine body size variation using resequencing data of miniature and large pigs. BMC Genomics 2018; 19: 687
- 7 Larzul C. Pig genetics: insight in minipigs. Bilateral Symposium on miniature pigs for biomedical research in Taiwan and France. 2013: 1-6 URL: https://hal.science/hal-00958583
- 8 Rozkot M, Václavcová E, Běková J. Minipigs as laboratory animals – review. Res Pig Breeding 2015; 9: 10-14 URL: http://www.respigbreed.cz/2015/2/3.pdf
- 9 McCrackin MA, Swindle MM. Chapter 1 Biology, Handling, Husbandry, and Anatomy. In: Swindle MM, Amith AC, eds. Swine in the laboratory. 3rd ed. Boca Raton: CRC Press; 2016: 1-38 ISBN: 978-1-4665-5352-1
- 10 Almaraj A, Matthijs A, Schoos A. et al. Health and management of hobby pigs: a review. Vlaams Diergeneeskundig Tijdschr 2018; 87: 347-358 URL: http://hdl.handle.net/1854/LU-8606323
- 11 Moß S. Das Minipig als Patient: Häufige Erkrankungen und Ursachen [Dissertation]. Hannover: Tierärztliche Hochschule Hannover; 2020. URL: https://elib.tiho-hannover.de/receive/tiho_mods_00001301
- 12 Busch B, Schlenker G. Merkblatt Nr. 94 – Artgemäße Haltung von Minipigs. Hrsg. TVT e.V. Bramsche; 2003: 1-10. URL: https://tierschutz-tvt.de/alle-merkblaetter-und-stellungnahmen/?no_cache=1&download=TVT-MB_94_Mini_Pigs__M%C3%A4rz_2003_.pdf&did=111
- 13 Woods AL, Tynes VV, Mozzacchio K. Chapter 13 Special consideration for show and pet pigs. In: Zimmerman JJ, Karriker LA, Ramirez A, Schwartz KJ, Stevenson GW, Zhang J, eds. Diseases of Swine. 11th ed. Hoboken: Wiley Blackwell; 2019: 211-220 ISBN: 978-1-119-35085-9
- 14 Howroyd PC, Peter B, de Rijk E. Review of sexual maturity in the minipig. Toxicol Pathol 2016; 44: 607-611
- 15 de Rijk E, van den Brink H, Lensen J. et al. Estrous cycle-dependent morphology in the reproductive organs of the female Göttingen minipig. Toxicol Pathol 42: 1197-1211
- 16 Hardge T, Koepke K, Reissmann M. et al. Maternal influences on litter size and growth in reciprocal crossed miniature pigs and durocs. Arch Anim Breed 1999; 42: 83-92
- 17 Skok J, Gerken M. Suckling strategies in the pig: the Göttingen minipig as a model. Livest Sci 2016; 184: 78-84
- 18 Søndergaard LV, Jensen KH, Hemmingsen R. et al. Characterisation of spontaneous behaviour in Göttingen minipigs in the home pen. Scand J Lab Anim Sci 2007; 34: 91-103
- 19 Tsutsumi H, Morikawa N, Niki R. et al. Acclimatization and response of minipigs toward humans. Lab Anim 2001; 35: 236-242
- 20 Gerencsér L, Pérez Fraga P, Lovas M. et al. Comparing interspecific socio-communicative skills of socialized juvenile dogs and miniature pigs. Anim Cogn 2019; 22: 917-929
- 21 Pérez Fraga P, Gerencsér L, Andics A. Human proximity seeking in family pigs and dogs. Sci Rep 2020; 10: 20883
- 22 Paredes-Ramos P, Diaz-Morales JV, Espinosa-Palencia M. et al. Clicker training accelerates learning of complex behaviours but reduces discriminative abilities of Yucatan miniature pigs. Animals 2020; 10: 959
- 23 Jønholt L, Bundegaard CL, Carlsen M. et al. A case study on the effect of positive reinforcement training in a novel task participation test in Göttingen mini pigs. Animals 2021; 11: 1610
- 24 Tynes VV, Hart BL, Bain MJ. Human-directed aggression in miniature pigs. J Am Vet Med Assoc 2007; 230: 385-389
- 25 Adcock SJJ, Martin GM, Walsh CJ. The stress response and exploratory behaviour in Yucatan minipigs (Sus scrofa): Relations to sex and social rank. Physiol Behav 2015; 152: 194-202
- 26 Baszczak J, Panepinto L, Grandin T. et al. Evaluation of stress and acclimation to new environments, procedures or equipment in Göttingen minipigs using behavioral and physiological stress indicators. Ellegaard Göttingen Minipigs: Dalmose, Denmark. 2018: 15-18 URL https://www.grandin.com/references/eval.stress.acclimations.new.items.gottingen.minipigs.pdf
- 27 Trappe H-J, Völkel E-M, Reiner G. Effekte von klassischer Musik oder von Heavy Metal bei Mensch und Tier: Implikationen für die Intensivmedizin. Med Klin Intensivmed Notfmed 2024; 1-12
- 28 Bayrischer Verwaltungsgerichtshof. Beschluss vom 22.12.2010 – 20 CS 10.2795. Fundstelle: openJur. 2012 112289. URL: https://openjur.de/u/487996.html
- 29 Bayrischer Verwaltungsgerichtshof. Beschluss vom 23.02.2012 – 20 ZB 11.2477. Fundstelle: openJur. 2012: 120770 URL: https://openjur.de/u/496333.html
- 30 Gillespie AV, Grove-White DH, Williams HJ. Husbandry, health and biosecurity of the smallholder and pet pig population in England. Vet Rec 2015; 177: 47
- 31 Boyle LA, Björklund L. Effects of fattening boars in mixed or single sex groups and split marketing on pig welfare. Anim Welf 2007; 16: 259-262
- 32 Verdon M, Morrison RS, Rice M. et al. The short-term behavioural response of sows, but not gilts, to a social stimulus is related to sow aggressiveness in groups. Behav Process 2017; 140: 216-225
- 33 Hyunh TTT. Heat stress in growing pigs [PhD Thesis]. Wageningen: Wageningen Institute of Animal Science; 2005. URL: https://edepot.wur.nl/121639
- 34 Mozzachio K. Chapter 3 Husbandry and nutrition. In: Mozzachio K, ed. Potbellied pig veterinary medicine. 1st ed. St. Louis: Elsevier; 2022: 26-38
- 35 Hessisches Ministerium für Umwelt, Klimaschutz, Landwirtschaft und Verbraucherschutz. Haltung von Minischweinen – Überblick über die rechtlichen Vorgaben. 2021; 1–6. URL https://umwelt.hessen.de/sites/umwelt.hessen.de/files/2021-10/merkblatt_zur_haltung_von_minischweinen_0.pdf
- 36 Ellegard L, Cunningham A, Edwards S. et al. Welfare of the minipig with special reference to use in regulatory toxicology studies. J Pharmacol Toxicol Methods 2010; 62: 167-183
- 37 Tynes VV. Potbellied pig husbandry and nutrition. Vet Clin North Am Exot Anim Pract 1999; 2: 193-208
- 38 Simon C, Kluge R. Fütterungskonzepte und -methoden aus der Versuchstierhaltung und im Tierversuch – Minipig. Hrsg. GV-SOLAS Freiburg; 2019: 1–11. URL https://www.gv-solas.de/wp-content/uploads/2019/09/Fuetterungskonzepte-Minipig-2019.pdf
- 39 Suzuki M, Sakurai K, Ozeki Y. et al. Studies on energy requirements of minipigs: energy requirements of shoats of pet minipigs. J Pet Anim Nutr 2006; 9: 82-90 fatcat:h7a67yfzanegfpqgvspdqzxd6y
- 40 Ritskes-Hoitinga J, Bollen P. Nutrition of (Göttingen) minipigs: facts, assumptions and mysteries. Pharmacol Toxicol 1997; 80: 5-9
- 41 Zhao X, Liu Y, Ding H. et al. Effects of different dietary protein levels on the growth performance, serum biochemical parameters, fecal nitrogen, and carcass traits of Huanjiang mini-pigs. Front Vet Sci 2021; 8: 777671
- 42 Bollen PJA, Madsen LW, Meyer O. et al. Growth differences of male and female Göttingen minipigs during ad libitum feeding: a pilot study. Lab Anim 2005; 39: 80-93
- 43 Minipigs EG. Taking good care of Ellegard Göttingen minipigs. Minipigs. 2013: 1-8 URL: https://minipigs.dk/sites/default/files/2021-06/Taking_good_care_of_Goettingen_Minipigs.pdf
- 44 Schanler RJ, Abrams SA, Sheng H-P. Calcium and phosphorus deficiencies affect mineral distribution in neonatal miniature piglets. Am J Clin Nutr 1991; 54: 420-424
- 45 Bollen PJA. Nutrition of Göttingen minipigs – a study of the influence of ad libitum and restricted feeding on the physiology of the Göttingen minipig [PhD Thesis]. Copenhagen: University of Southern Denmark; 2001. URL: https://www.researchgate.net/profile/Peter-Bollen/publication/342171444_Nutrition_of_Gottingen_Minipigs_-_A_study_of_the_influence_of_ad_libitum_and_restricted_feeding_on_the_physiology_of_the_Gottingen_minipig/links/5ee7511d92851ce9e7e3c80a/Nutrition-of-Goettingen-Minipigs-A-study-of-the-influence-of-ad-libitum-and-restricted-feeding-on-the-physiology-of-the-Goettingen-minipig.pdf
- 46 Scholz-Ahrens KE, Glüer C-C, Bronner F. et al. Modulation of Vitamin D status and dietary calcium affects bone mineral density and mineral metabolism in Göttingen minipigs. ISRN Rheumatology 2013; Article ID 460512
- 47 Delesalle C, Dewulf J, Lefebvre RA. et al. Use of plasma ionized calcium levels and Ca2+ substitution response patterns as prognostic parameters for ileus and survival in colic horses. Vet Quart 2005; 27: 157-172
- 48 Ounissi M, Gargueh T, Mahfoudhi M. et al. Nephrolithiasis-induced end stage renal disease. Int J Nephrol Renov Dis 2010; 3: 21-26
- 49 Lechner M. Wie wählen Nutztiere ihre Nahrung aus? Verhalten ist kein Selbstzweck – Betrachtung der Zusammenhänge aus praktischer Sicht. Deutsches Tierärzteblatt 2024; 72: 166-172 URL: https://www.bundestieraerztekammer.de/btk/dtbl/archiv/2024/artikel/DTBl_02_2024_Nahrungsauswahl.pdf
- 50 Nakamae Y, Hobbs KJ, Ziegler J. et al. Gastrointestinal foreign bodies in pet pigs: 17 cases. J Vet Intern Med 2022; 36: 1185-1189
- 51 van Amstel S, Doherty T. Claw horn growth and wear rates, toe length, and claw size in commercial pigs: a pilot study. J Swine Health Prod 2010; 18: 239-243 URL https://www.aasv.org/shap/issues/v18n5/v18n5p239.pdf
- 52 van Amstel S. Lower leg lameness in swine. In: Proceedings of the NAVC Conference; Orlando, 15th–19th January. 2011; 342-345 URL https://www.cabidigitallibrary.org/doi/pdf/10.5555/20113159322
- 53 Newman SJ, Rohrbach BW, Wilson ME. et al. Characterization of histopathologic lesions among pigs with overgrown claws. J Swine Health Prod 2015; 23: 91-96 URL https://www.aasv.org/shap/issues/v23n2/v23n2p91.pdf
- 54 Wilkinson LM, OʼMalley CI, Moreau E. et al. Using stakeholder focus groups to refine the care of pigs used in research. J Am Assoc Anim Lab Anim Sci 2023; 62: 123-130
- 55 Mozzachio K. Chapter 7 Routine procedures. In: Mozzachio K, ed. Potbellied pig veterinary medicine. 1st ed. St. Louis: Elsevier; 2022: 73-100
- 56 Tomlinson DJ, Mülling CH, Fakler TM. Invited Review: Formation of keratins in the bovine claw: roles of hormones, minerals, and vitamins in functional claw integrity. J Dairy Sci 2004; 87: 797-809
- 57 Mülling CKW, Bragulla HH, Reese S. et al. How structures in bovine hoof epidermis are influenced by nutritional factors. Anat Histol Embryol 1999; 28: 103-108
- 58 Bryant KL, Kornegay ET, Knight JW. et al. Supplemental biotin for swine. I. Influence on feedlot performance, plasma biotin and toe lesions in developing gilts. J Anim Sci 1985; 60: 136-144
- 59 Kopinski JS, Leibholz J, Bryden WL. et al. Biotin studies in pigs. 1. Biotin deficiency in young pig. Br J Nutr 1989; 62: 751-759
- 60 Hay M, Rue J, Sansac C. et al. Long-term detrimental effects of tooth clipping or grinding in piglets: a histological approach. Anim Welf 2004; 13: 27-32
- 61 Savard C, Dumais Y, Pouillevet H. et al. Extraction of aberrant tusk and mandibular osteomyelitis treatment in a pot-bellied pig (Sus scrofa domesticus) . J Exot Pet Med 2021; 39: 24-31
- 62 Mozzachio K. Chapter 6 Physical exam. In: Mozzachio K, ed. Potbellied pig veterinary medicine. 1st ed. St. Louis: Elsevier; 2022: 58-72
- 63 Carr J, Wilbers A. Pet pig medicine. 1. The normal pig. In Practice 2008; 30: 160-166
- 64 Chang J, Jung J, Oh S. et al. Evaluation of normal abdominal organs by diagnostic imaging in the premature miniature pig. J Life Sci 2009; 19: 417-421
- 65 Takasu M, Tsuji E, Imaeda N. et al. Body and major organ sizes of young mature microminipigs determined by computed tomography. Lab Anim 2015; 49: 65-70
- 66 Huppertz ND, Tolba RH, Grosse JO. Micturition in Göttingen minipigs: first reference in vivo data for urological research and review of literature. Lab Anim 2015; 49: 336-344
- 67 Reiner G. Krankes Schwein, kranker Bestand. 1. Aufl. Stuttgart: Eugen Ulmer; 2015. ISBN: 9783825286460
- 68 Grandin T. Minimizing stress in pig handling in the research lab. Lab Animal 1986; 15: 15-20 URL https://www.grandin.com/references/minimizing.stress.in.pig.handling.html
- 69 Marchant-Forde JN, Herskin MS. Pigs as laboratory animals. In: Špinka M, ed. Advances in Pig Welfare. Cambridge: Woodhead Publishing; 2018: 445-475
- 70 Theil PK, Pedersen LJ, Jensen MB. et al. Blood sampling and hemolysis affect concentration of plasma metabolites. J Anim Sci 2012; 90: 412-414
- 71 Dubreuil P, Couture Y, Tremblay A. et al. Effects of experimenters and different blood sampling procedures on blood metabolite values in growing pigs. Can J Vet Res 1990; 54: 379-382 URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1255673/
- 72 Tynes VV, Mozzachio K. Chapter 12 Miniature pigs. In: Carpenter JW, Marion CJ, eds. Exotic animal formulary. 5th ed. St. Louis: Elsevier; 2018: 799-822
- 73 Brockus CW, Mahaffey EA, Bush SE. et al. Hematologic and serum biochemical reference intervals for Vietnamese potbellied pigs (Sus scrofa). Comp Clin Path 2005; 13: 162-165
- 74 Helke KL, Ezell PC, Duran-Struuck R. et al. Chapter 16 Biology and diseases of swine. In: Fox JG, Anderson LC, Otto GM, Pritchett-Corning KR, Whary MT, eds. Laboratory Animal Medicine. 3rd ed. St. Louis: Elsevier; 2015: 695-769
- 75 Min F, Pan J, Wang X. et al. Biological characteristics of captive Chinese Wuzishan minipigs (Sus scrofa). Int Sch Res Notices 2014; 761257
- 76 Clark SG, Coffer N. Normal hematology and hematologic disorders in potbellied pigs. Vet Clin Exot Anim 2008; 11: 569-582
- 77 Christofferson BØ, Jensen SJ, Ludvigsen TP. et al. Age- and Sex-associated effects on acute-phase proteins in Göttingen minipigs. Comp Med 2015; 65: 333-341 URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549679/
- 78 Emmerich IU. Haltererklärung – für welche Tiere ist sie nach derzeitiger Rechtslage zulässig?. Amtstierärztlicher Dienst und Lebensmittelkontrolle 2014; 21: 116-118
- 79 Emmerich I, Sommerhäuser J. Das neue Tierarzneimittelrecht: Erläuterungen zur neuen Rechtssystematik, Umwidmungskaskade und Festlegung der Mindestwartezeit. Deutsches Tierärzteblatt 2022; 70: 14-20 URL https://www.bundestieraerztekammer.de/btk/dtbl/archiv/2022/artikel/DTBl_01_2022_Tierarzneimittelrecht.pdf
- 80 Posner LP. Chapter 8 Sedation and anesthesia. In: Mozzachio K, ed. Potbellied pig veterinary medicine. 1st ed. St. Louis: Elsevier; 2022: 101-114
- 81 Universität Leipzig. VETIDATA - Veterinärmedizinischer Informationsdienst für Arzneimittelanwendung, Toxikologie und Arzneimittelrecht (April 2024). Im Internet www.vetidata.de; Stand: 03.04.2024
- 82 Herskin MS, Di Giminiani P. Chapter 11 Pain in pigs – Characterization, mechanisms and indicators. In: Špinka M, ed. Advances in pig welfare. 1st ed. Sawston: Woodhead Publishing; 2017: 325-355
- 83 Viscardi AV, Hunniford M, Lawlis P. et al. Development of a piglet grimace scale to evaluate piglet pain using facial expressions following castration and tail docking: a pilot study. Front Vet Sci 2017; 4: 51
- 84 Lou ME, Porter ST, Massey JS. et al. The application of 3D landmark-based geometric morphometrics towards refinement of the piglet grimace scale. Animals 2022; 12: 1944
- 85 Carr J, Wilbers A. Pet pig medicine. 2. The sick pig. In Practice 2008; 30: 214-221
- 86 Johanson T, Hansen HS, Richelsen B. et al. The obese Göttingen minipig as a model of the metabolic syndrome: dietary effects on obesity, insulin sensitivity, and growth hormone profile. Comp Med 2001; 51: 150-155 URL https://www.ingentaconnect.com/content/aalas/cm/2001/00000051/00000002/art00009?crawler=true&mimetype=application/pdf
- 87 Newell-Fugate AE, Taibl JN, Clark SG. et al. Effects of diet-induced obesity on metabolic parameters and reproductive function in female Ossabaw minipigs. Comp Med 2014; 64: 44-49 URL https://www.ingentaconnect.com/content/aalas/cm/2014/00000064/00000001/art00005?crawler=true
- 88 Luo H-Q, Gu W-W, Huang L-W. et al. Effect of pregnancy obesity on litter size in primiparous minipigs. J Am Assoc Lab Anim Sci 2018; 57: 115-123 URL: https://www.ingentaconnect.com/contentone/aalas/jaalas/2018/00000057/00000002/art00004?crawler=true
- 89 Pedersen R, Ingerslev H-C, Sturek M. et al. Characterisation of gut microbiota in Ossabaw and Göttingen minipigs as models of obesity and metabolic syndrome. Plos One 2013; 8: e56612
- 90 Xia J, Zhang Y, Xin L. et al. Global transcriptomic profiling of cardiac hypertrophy and fatty heart induced by long-term high-energy diet in Bama miniature pigs. Plos One 2015; 10: e0132420
- 91 Wang C-Y, Li S-J, Wu T-W. et al. The role of pericardial adipose tissue in the heart of obese minipigs. Eur J Clin Invest 2018; 48: e12942
- 92 Månsson I, Norberg R, Olhagen B. et al. Arthritis in pigs induced by dietary factors. Microbiologic, clinical and histologic studies. Clin Exp Immunol 1971; 9: 677-693 URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1713057/
- 93 Lonergan RP, Ware JC, Atkinson RL. et al. Sleep apnea in obese miniature pigs. J Appl Physiol 1998; 84: 531-536
- 94 Allbaugh RA, Davidson HJ. Surgical correction of periocular fat pads and entropion in a potbellied pig (Sus scrofa). Vet Ophthalmol 2009; 12: 115-118
- 95 Claasen H, Hornberger F, Scholz-Ahrens K. et al. The effect of estrogens and dietary calcium deficiency on the extracellular matrix of articular cartilage in Göttingen miniature pigs. Ann Anat 2002; 184: 141-148
- 96 Abrams SA, Schanler RJ, Sheng H-P. et al. Bone mineral content reflects total body calcium in neonatal miniature piglets. Pediatr Res 1988; 24: 693-695
- 97 Limeback H, Schlumbohm C, Sen A. et al. The effects of hypocalcemia/hypophosphatemia on porcine bone and dental hard tissues in an inherited form of type 1 pseudo-vitamin D deficiency rickets. J Dent Res 1992; 71: 346-352
- 98 Madson DM, Ensley SM, Gauger PC. et al. Rickets: case series and diagnostic review of hypovitaminosis D in swine. J Vet Diagn Invest 2012; 24: 1137-1144
- 99 Walker A, el Demellawy D, Davila J. Rickets: historical, epidemiological, pathophysiological, and pathological perspectives. Acad Forensic Pathol 2017; 7: 240-262
- 100 van Riet MMJ, Millet S, Aluwé M. et al. Impact of nutrition on lameness and claw health in sows. Livest Sci 2013; 156: 24-35
- 101 Ytrehus B, Carlson CS, Ekman S. Etiology and pathogenesis of osteochondrosis. Vet Pathol 2007; 44: 429-448
- 102 Varagka N, Lisgara M, Skampardonis V. et al. Pathological evaluation of claw lesions in culled sows from a Greek herd. J Swine Health Prod 2016; 24: 72-80 URL https://www.aasv.org/shap/issues/v24n2/v24n2p72.html
- 103 Reiner G, Holweger K, Hertrampf B. et al. Operative Therapie eines Rezidivileus mit hämorrhagischer Dünndarmnekrose bei einem Miniaturschwein. Tierärztl Prax Ausg K Kleintiere Heimtiere 2006; 34: 361-365
- 104 Ludwig EK, Byron CR. Evaluation of the reasons for and outcomes of gastrointestinal tract surgery in pet pigs: 11 cases (2004-2015). J Am Vet Med Assoc 2017; 251: 714-721
- 105 Hobbs KJ, DeNotta SL, Gallastegui A. et al. Obstipation in pet pigs: 24 cases. Can Vet J 2021; 62: 843-848 URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281943/
- 106 Chigerwe M, Shiraki R, Olstad EC. et al. Mineral composition of urinary calculi from potbellied pigs with urolithiasis: 50 cases (1982-2012). J Am Vet Med Assoc 2013; 243: 389-393
- 107 Coutant T, Dunn M, Montasell X. et al. Use of percutaneous cystolithotomy for removal of urethral uroliths in a pot-bellied pig. Can Vet J 2018; 59: 159-164 URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764218/
- 108 Marcodes I, Rodrigues N, Massonie EA. et al. Urolitíase em suíno: Relato de caso. Pubvet 2022; 16: a1273
- 109 Simpson KM, Oman RE, Depenbrock SM. Diagnosis and management of obstructive urolithiasis in miniature pigs. J Am Vet Med Assoc 2022; 260: S72-S79
- 110 Ullrich T, Jäger AK, Große R. et al. Präpubische Urethrostomie bei einem Wiesenauer Minischwein mit Urolithiasis. Tierärztl Prax Ausg G Großtiere Nutztiere 2022; 50: 200-206
- 111 Needleman A, Videla R. Urolithiasis in female miniature potbellied pig. Vet Rec Case Rep 2019; 7: e000809
- 112 Mozzachio K. Chapter 10 Illness and disease. In: Mozzachio K, ed. Potbellied pig veterinary medicine. 1st ed. St. Louis: Elsevier; 2022: 129-212
- 113 Morrow JL. Hepatocellular carcinoma and suspected splenic hemangiosarcoma in a potbellied pig. Can Vet J 2002; 43: 466-468 URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC339301/
- 114 Ilha MRS, Newman SJ, van Amstel S. et al. Uterine Lesions in 32 female miniature pet pigs. Vet Pathol 2010; 47: 1071-1075
- 115 Höltig D, Nickoll I, Kauffold J. et al. Uterustumore bei älteren Miniaturschweinen – Diagnostik und Therapie. Tierärztl Prax Ausg K Kleintiere Heimtiere 2015; 43: 427-433
- 116 Dürlinger S, Knecht C, Gumpenberger M. et al. Cystic endometrial hyperplasia and uterine adenocarcinoma in two miniature pigs. Tierärztl Prax Ausg G Grosstiere Nutztiere 2022; 50: 333-339
- 117 Misdorp W. Congenital and hereditary tumours in domestic animals. 2. Pigs. A review. Vet Q 2003; 25: 17-30
- 118 Weyrich A, Becker S, Vienenkötter J. et al. A rare case of multicentric eosinophilic granulocytic sarcoma as cause of hindlimb weakness and non-regenerative anaemia in a minipig. Vet Rec Case Rep 2021; 9: e133
- 119 Mitchell J, Tinkey PT, Avritscher R. et al. Validation of a preclinical model of diethylnitrosamine-induced hepatic neoplasia in Yucatan miniature pigs. Oncology 2016; 91: 90-100
- 120 Cypher E, Videla R, Pierce R. et al. Clinical prevalence and associated intraoperative surgical complications of reproductive tract lesions in pot-bellied pigs undergoing ovariohysterectomy: 298 cases (2006–2016). Vet Rec 2017; 181: 685
- 121 Corapi WV, Rodrigues A, Lawhorn DB. Mucinous adenocarcinoma and T-cell lymphoma in the small intestine of 2 Vietnamese potbellied pigs (Sus scrofa). Vet Pathol 2011; 48: 1004-1007
- 122 Swenson J, Carpenter JW, Ragsdale J. et al. Oral squamous cell carcinoma in a Vietnamese pot-bellied pig (Sus scrofa). J Vet Diagn Invest 2009; 21: 905-909
- 123 Preissel A-K, Brugger N, Stassen T. et al. Behandlung eines Uterusadenokarzinoms eines Minipigs durch Ovariohysterektomie. Schweiz Arch Tierheilk 2009; 151: 229-232
- 124 Sipos W, Hirschberger J, Breuer W. et al. Partial remission of mast cell leukaemia in a minipig after chemotherapy. Vet Rec 2010; 166: 791-793
- 125 Payne JT, Braun WF, Anderson DE. et al. Articular fractures of the distal portion of the humerus in Vietnamese pot-bellied pigs: six cases (1988-1992). J Am Vet Med Assoc 1995; 206: 59-62
- 126 Høy-Petersen J, Smith JS, Merkatoris PT. et al. Case report: trochlear wedge sulcoplasty, tibial tuberosity transposition, and lateral imbrication for correction of a traumatic patellar luxation in a miniature companion pig: a case report and visual description. Front Vet Sci 2021; 7: 567886
- 127 Halecker S, Metzger J, Strube C. et al. Virological and parasitological characterization of Mini-LEWE minipigs using improved screening methods and an overview of data on various minipig breeds. Microorganisms 2021; 9: 2617
- 128 Stærk K, Andersen MØ, Andersen TE. Uropathogenic Escherichia coli can cause cystitis at extremely low inocula in a pig model. J Med Microbiol 2022; 71: 001537
- 129 Salcedo-Jiménez R, Brounts SH, Mulon P-Y. et al. Multicenter retrospective study of complications and risk factors associated with castration in 106 pet pigs. Can Vet J 2020; 61: 173-177 URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973211/
- 130 Østevik L, Elmas C, Rubio-Martinez LM. Castration of the Vietnamese pot-bellied boar: 8 cases. Can Vet J 2012; 53: 943-948 URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418779/
- 131 Skelton JA, Baird AN, Hawkins JF. et al. Cryptorchidectomie with a paramedian or inguinal approach in domestic pigs: 47 cases (2000-2018). J Am Vet Med Assoc 2021; 258: 1130-1134
- 132 Rosanova N, Singh A, Cribb N. Laparoscopic-assisted cryptorchidectomy in 2 Vietnamese pot-bellied pigs (Sus scrofa). Can Vet J 2015; 56: 153-156 URL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298267/
- 133 Richard HR, Clemens N, Reiner G. Die Kastration weiblicher Miniaturschweine. Tierärztl Prax Ausg K Kleintiere Heimtiere 2009; 37: 396-398
- 134 Pendl W, von Ah S, Keller S. et al. Der Kaiserschnitt beim Miniaturschwein – Ein Fallbericht. Prakt Tierarzt 2019; 100: 70-77
- 135 Grahofer A, Bannoehr J, Nathues H. et al. Sarcoptes infestation in two miniature pigs with zoonotic transmission – a case report. BMC Vet Res 2018; 14: 91
- 136 Schwarz L, Herb V, Dürlinger S. et al. Demodicosis in a Kunekune pig and molecular characterisation of porcine demodectic mites involved: a case report. Parasit Vectors 2024; 17: 32
- 137 Stricker-Krongrad A, Shoemake CR, Liu J. et al. The importance of minipigs in dermal safety assessment: an overview. Cutan Ocul Toxicol 36: 105-113
- 138 Jhelum H, Grand N, Rosenmay K. et al. First virological and pathological study of Göttingen minipigs with Dippity Pig Syndrome (DPS). Plos One 2023; 18: e0281521
- 139 Robinson NA, Loynachan AT. Chapter 14 Cardiovascular and hematopoietic systems. In: Zimmerman JJ, Karriker LA, Ramirez A, Schwartz KJ, Stevenson GW, Zhang J, eds. Diseases of Swine. 11th ed. Hoboken: Wiley Blackwell; 2019: 223-233 ISBN: 978-1-119-35085-9
- 140 Schikowski L, Schaub S, Thalmeier S. et al. Imaging findings in a minipig with congenital portosystemic shunt. Tierärztl Prax Ausg K Kleintiere Heimtiere 2022; 50: 370-375
- 141 Maratea KA, Snyder PW, Stevenson GW. Vascular lesions in nine Göttingen minipigs with thrombocytopenic purpura syndrome. Vet Pathol 2006; 43: 447-454
- 142 Yaeger MJ, Van Alstine WG. Chapter 21 Respiratory System. In: Zimmerman JJ, Karriker LA, Ramirez A, Schwartz KJ, Stevenson GW, Zhang J, eds. Diseases of Swine. 11th ed. Hoboken: Wiley Blackwell; 2019: 393-407 ISBN: 978-1-119-35085-9
- 143 Iwatsuki-Horimoto K, Nakajima N, Shibata M. et al. The microminipig as an animal model for influenza A virus infection. J Virol 2016; 91: e01716-e01716
- 144 Gan Y, Xie X, Zhang L. et al. Establishment of a model of Mycoplasma hyopneumoniae infection using Bama miniature pigs. Food Prod Proc Nutr 2020; 2: 19
- 145 Williams PP. Study of immune function in inbred miniature pigs vaccinated and challenged with Suid Herpesvirus 1. Can J Vet Res 1995; 59: 285-293 URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1263783/
- 146 Thirwall RE, Commander NJ, Brew SD. et al. Improving the specifity of immunodiagnosis for porcine brucellosis. Vet Res Commun 2008; 32: 209-213
- 147 Lv C, Yang J, Zhao L. et al. Infection characteristics and transcriptomics of African Swine Fever Virus in Bama minipigs. Microbiol Spectr 2022; 10: e03834-22
- 148 Sun Y, Jiang Q, Tian D-Y. et al. Experimental infection of Bama miniature pigs with a highly virulent classical swine fever virus. Virol J 2011; 8: 452